ArticleBMC evolutionary biology2008
The prevalence of genome replacement in unisexual salamanders of the genus Ambystoma (Amphibia, Caudata) revealed by nuclear gene genealogy.
Article in BMC evolutionary biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
- Spatio-Temporal Patterns of Hybridization in an Alloploid Salamander (Ambystomatidae:Ecology and evolution · 2025Article
- Sperm-dependent asexual species and their role in ecology and evolution.Ecology and evolution · 2023Review
- Sex chromosomes in meiotic, hemiclonal, clonal and polyploid hybrid vertebrates: along the 'extended speciation continuum'.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Survival of Polyploid hybrid salamander embryos.BMC developmental biology · 2019Article
- Effect of a locally adapted genome on environmentally induced epigenetic variation.Environmental epigenetics · 2018Article
- Influence of genome and bio-ecology on the prevalence of genome exchange in unisexuals of the Ambystoma complex.BMC evolutionary biology · 2018Article
- Genome Expression Balance in a Triploid Trihybrid Vertebrate.Genome biology and evolution · 2017Article
- Rapid genomic DNA changes in allotetraploid fish hybrids.Heredity · 2015Article
- The evolutionary history of the allopolyploid Squalius alburnoides (Cyprinidae) complex in the northern Iberian Peninsula.Heredity · 2011Article
- Time and time again: unisexual salamanders (genus Ambystoma) are the oldest unisexual vertebrates.BMC evolutionary biology · 2010Article
- Probing the meiotic mechanism of intergenomic exchanges by genomic in situ hybridization on lampbrush chromosomes of unisexual Ambystoma (Amphibia: Caudata).Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2010Article
- Gamete types, sex determination and stable equilibria of all-hybrid populations of diploid and triploid edible frogs (Pelophylax esculentus).BMC evolutionary biology · 2009Article
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3 authors.
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Abstract
backgroundUnisexual salamanders of the genus Ambystoma exemplify the most ancient lineage of unisexual vertebrates and demonstrate an extremely flexible reproductive system. Unisexual Ambystoma interact with and incorporate genomes from two to four sexual species (A. laterale, A. jeffersonianum,A. texanum, and A. tigrinum), to generate more than 20 genome compositions or biotypes. Unisexual ploidy levels range from diploid to pentaploid, but all contain at least one A. laterale (L) genome. Replacement of nuclear genomes might be responsible for the evolutionary longevity of unisexual Ambystoma but direct evidence for the prevalence of genome replacement in natural populations is absent. Two major puzzling questions have remained unanswered over the last few decades: 1) is genome replacement a common reproductive method in various unisexual populations and, 2) is there an ancient "L" genome that persists in various unisexual genome compositions.
resultsWe examined 194 unisexual and 89 A. laterale specimens from 97 localities throughout their range and constructed a genealogy of the "L" genomes using a nuclear DNA marker (L-G1C12) to answer the above questions. Six L-G1C12 haplotypes (A-F) were shared by individuals in various A. laterale and unisexual populations. The general geographical distribution of the haplotypes in unisexual populations conformed to those found in A. laterale, indicating that "L" genomes in unisexuals are obtained from sympatric or nearby populations of A. laterale.
conclusionOur data demonstrate that genome replacement frequently occurs in unisexual Ambystoma across their range, and support previous speculations that genome replacement is an important reproductive mechanism that can enhance their evolutionary longevity. Our results show that there is no ancient "L" genome in the unisexual lineages, and no particular "L" genome is favored in any unisexual individual. The presence of an "L" genome in all unisexuals implies that it is important to the maintenance of unisexuals. Nuclear gene genealogy is a powerful tool to examine the historical interaction between sperm-dependent unisexuals and their sexual sperm donors. This methodology could be applicable to many other unisexual lineages to improve our understanding of their reproduction and their ability to persist.
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