ArticlePLoS genetics2008
Inferring human colonization history using a copying model.
Article in PLoS genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Dense sampling of ethnic groups within African countries reveals fine-scale genetic structure and extensive historical admixture.Science advances · 2023Article
- Structure and ancestry patterns of Ethiopians in genome-wide autosomal DNA.Human molecular genetics · 2021Review
- Scalable probabilistic PCA for large-scale genetic variation data.PLoS genetics · 2020Article
- African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations.Genome biology · 2019Article
- Distinguishing the victim from the threat: SNP-based methods reveal the extent of introgressive hybridization between wildcats and domestic cats in Scotland and inform future in situ and ex situ management options for species restoration.Evolutionary applications · 2019Article
- The Genetic Legacy of Zoroastrianism in Iran and India: Insights into Population Structure, Gene Flow, and Selection.American journal of human genetics · 2017Article
- A performance study of the impact of recombination on species tree analysis.BMC genomics · 2016Article
- Article
- A probabilistic method for testing and estimating selection differences between populations.Genome research · 2015Article
- Two molecular measures of relatedness based on haplotype sharing.BMC bioinformatics · 2015Article
- Evidence for a Common Origin of Blacksmiths and Cultivators in the Ethiopian Ari within the Last 4500 Years: Lessons for Clustering-Based Inference.PLoS genetics · 2015Article
- Article
- Inferring population structure and demographic history using Y-STR data from worldwide populations.Molecular genetics and genomics : MGG · 2015Article
- Relatedness in the post-genomic era: is it still useful?Nature reviews. Genetics · 2015Review
- The peopling of the African continent and the diaspora into the new world.Current opinion in genetics & development · 2014Review
- Toward a new history and geography of human genes informed by ancient DNA.Trends in genetics : TIG · 2014Review
- Spatial and temporal simulation of human evolution. Methods, frameworks and applications.Current genomics · 2014Article
- Reconciling migration models to the Americas with the variation of North American native mitogenomes.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- A sequentially Markov conditional sampling distribution for structured populations with migration and recombination.Theoretical population biology · 2013Article
- Genome-wide diversity in the levant reveals recent structuring by culture.PLoS genetics · 2013Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
Genome-wide scans of genetic variation can potentially provide detailed information on how modern humans colonized the world but require new methods of analysis. We introduce a statistical approach that uses Single Nucleotide Polymorphism (SNP) data to identify sharing of chromosomal segments between populations and uses the pattern of sharing to reconstruct a detailed colonization scenario. We apply our model to the SNP data for the 53 populations of the Human Genome Diversity Project described in Conrad et al. (Nature Genetics 38,1251-60, 2006). Our results are consistent with the consensus view of a single "Out-of-Africa" bottleneck and serial dilution of diversity during global colonization, including a prominent East Asian bottleneck. They also suggest novel details including: (1) the most northerly East Asian population in the sample (Yakut) has received a significant genetic contribution from the ancestors of the most northerly European one (Orcadian). (2) Native North [corrected] Americans have received ancestry from a source closely related to modern North-East Asians (Mongolians and Oroquen) that is distinct from the sources for native South [corrected] Americans, implying multiple waves of migration into the Americas. A detailed depiction of the peopling of the world is available in animated form.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.