ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2008
Increased dopamine level enhances male-male courtship in Drosophila.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 91 citations in OpenAlex.
- Dopamine and its receptoreLife · 2026Article
- Dopamine Enhances Healthspan and Locomotor Performance via Antioxidant Defense in Silkworms,Insects · 2026Article
- A Hypersexuality Subset Behavior Induced by Aripiprazole Overdose in an Antipsychotic Naïve Patient: A Case Report and Review of the Literature.Clinics and practice · 2026Article
- Differential dopaminergic modulation of the antennal lobe of Drosophila melanogaster.Communications biology · 2025Article
- The non-nuclear DifB NF-κB isoform affects courtship, circadian, and locomotor behavior in adultFrontiers in behavioral neuroscience · 2025Article
- Biological, genetic, neurological and environmental influences on homosexuality-a narrative review.Frontiers in behavioral neuroscience · 2025Review
- The Chromosome-level Genome Provides Insights into the Evolution and Adaptation of Extreme Aggression.Molecular biology and evolution · 2024Article
- Intense light unleashes male-male courtship behaviour in wild-typeOpen biology · 2023Article
- Drosophila mutants lacking the glial neurotransmitter-modifying enzyme Ebony exhibit low neurotransmitter levels and altered behavior.Scientific reports · 2023Article
- The Drosophila dopamine 2-like receptor D2R (Dop2R) is required in the blood brain barrier for male courtship.Genes, brain, and behavior · 2023Article
- Investment Trade-Off between Mating Behavior and Tonic Immobility in the Sweetpotato WeevilInsects · 2023Article
- Myc suppresses male-male courtship in Drosophila.The EMBO journal · 2022Article
- The modulatory effects of biogenic amines on male mating performance inFrontiers in physiology · 2022Article
- Trade-off Investment between Tonic Immobility and Mate Search in the Sweetpotato Weevil,Insects · 2020Article
- The depletion of ubiquilin in Drosophila melanogaster disturbs neurochemical regulation to drive activity and behavioral deficits.Scientific reports · 2020Article
- The Neurotransmitters Involved inFrontiers in behavioral neuroscience · 2020Review
- Drosophila as a Model System for Neurotransmitter Measurements.ACS chemical neuroscience · 2018Review
- Big Lessons from Tiny Flies:International journal of molecular sciences · 2018Review
- Modulation of social space by dopamine inBiology letters · 2017Article
- Active and passive sexual roles that arise in Drosophila male-male courtship are modulated by dopamine levels in PPL2ab neurons.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sexual behavior between males is observed in many species, but the biological factors involved are poorly known. In mammals, manipulation of dopamine has revealed the role of this neuromodulator on male sexual behavior. We used genetic and pharmacological approaches to manipulate the dopamine level in dopaminergic cells in Drosophila and investigated the consequence of this manipulation on male-male courtship behavior. Males with increased dopamine level showed enhanced propensity to court other males but did not change their courtship toward virgin females, general olfactory response, general gustatory response, or locomotor activity. Our results indicate that the high intensity of male-male interaction shown by these manipulated males was related to their altered sensory perception of other males.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.