Evidence map›Paper›PMID 18495050›Full record

ArticleCritical care (London, England)2008

Moving beyond tight glucose control to safe effective glucose control.

James S Krinsley, Jean-Charles Preiser

Open access · goldAbstract read
In one paragraph

Article in Critical care (London, England), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Plasma-generating glucose monitor accuracy demonstrated in an animal model.Journal of diabetes science and technology · 2009
    Article
  13. Review
  14. Year in review 2008: Critical Care--metabolism.Critical care (London, England) · 2009
    Review
  15. NICE-SUGAR: the end of a sweet dream?Critical care (London, England) · 2009
    Article
  16. Current status of tight blood sugar control.Current infectious disease reports · 2008
    Article
  17. Article
  18. Is "safe effective glucose control" effective and safe?Critical care (London, England) · 2008
    Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

James S KrinsleyDivision of Critical Care, Stamford Hospital, 190 West Broad Street, Stamford, CT 06902, USA.
Jean-Charles Preiser
Centre Hospitalier Universitaire de Liège · BEStamford Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impressive benefits related to the use of tight glucose control by intensive insulin therapy have not been reproduced until now in multicenter large-scale prospective randomized trials. Although the reasons for these failures are not entirely clear, we suggest the use of a stepwise approach - Safe, Effective Glucose Control - that will essentially target an intermediate blood glucose level. As compared with genuine tight glucose control, Safe, Effective Glucose Control - already used in many intensive care units worldwide - is intended to decrease the rate of hypoglycemia and the workload, while reducing the adverse effects of severe hyperglycemia.

Indexed as

Critical CareBlood GlucoseHumansHypoglycemiaInsulinMonitoring, PhysiologicBlood GlucoseInsulin

Identifiers

PMID18495050
PMCPMC2481442
OpenAlexW2058357038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.