Evidence map›Paper›PMID 18494840›Full record

Trial reportAddiction (Abingdon, England)2008

Effects of behavioral intervention on substance use among people living with HIV: the Healthy Living Project randomized controlled study.

F Lennie Wong, Mary Jane Rotheram-Borus, Marguerita Lightfoot, Willo Pequegnat, W Scott Comulada, William Cumberland, Lance S Weinhardt, Robert H Remien, Margaret Chesney, Mallory Johnson and 1 more

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Addiction (Abingdon, England), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  11. Article
  12. The Mental Health of Older LGBT Adults.Current psychiatry reports · 2016
    Review
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  20. Relationships over time between mental health symptoms and transmission risk among persons living with HIV.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

F Lennie WongUniversity of California, Los Angeles, CA, USA.
Mary Jane Rotheram-Borus
Marguerita Lightfoot
Willo Pequegnat
W Scott Comulada
William Cumberland
Lance S Weinhardt
Robert H Remien
Margaret Chesney
Mallory Johnson
Healthy Living Trial Group
University of California, Los Angeles · USUniversity of California, San Francisco · USMedical College of Wisconsin · USNational Institute of Mental Health · USNew York Psychoanalytic Society and Institute · US

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
Virology CoreP30AI028697 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ANTON, PETER A · 1991 to 2018
$39.9M
HEALTH RELATED INTERVENTIONS FOR PERSONS LIVING WITH HIVU10MH057615 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY J · 2001 to 2004
$5.2M
HEALTH RELATED INTERVENTIONS FOR PERSONS LIVING WITH HIVU10MH057636 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE · PI EHRHARDT, ANKE A · 2001 to 2004
$3.5M
HEALTH RELATED INTERVENTIONS FOR PERSONS LIVING WITH HIVU10MH057616 · NIMH · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI MORIN, STEPHEN F · 2001 to 2004
$2.9M
HEALTH RELATED INTERVENTIONS FOR PERSONS LIVING WITH HIVU10MH057631 · NIMH · MEDICAL COLLEGE OF WISCONSIN · PI KELLY, JEFFREY A. · 2001 to 2004
$2.2M
NIAID NIH HHS P30 AI028697NIMH NIH HHS P30 MH043520NIMH NIH HHS U10 MH057615NIMH NIH HHS U10MH057615NIMH NIH HHS U10 MH057616NIMH NIH HHS U10MH057616NIMH NIH HHS U10 MH057631NIMH NIH HHS U10MH057631NIMH NIH HHS U10 MH057636NIMH NIH HHS U10MH057636
6 · The paper itself

Abstract

aimReductions in substance use were examined in response to an intensive intervention with people living with human immunodeficiency virus (HIV) (PLH). DESIGN, SETTING AND

participantsA randomized controlled trial was conducted with 936 PLH who had recently engaged in unprotected sexual risk acts recruited from four US cities: Milwaukee, San Francisco, New York and Los Angeles. Substance use was assessed as the number of days of use of 19 substances recently (over the last 90 days), evaluated at 5-month intervals over 25 months.

interventionA 15-session case management intervention was delivered to PLH in the intervention condition; the control condition received usual care. MEASUREMENTS: An intention-to-treat analysis was conducted examining reductions on multiple indices of recent substance use calculated as the number of days of use.

findingsReductions in recent substance use were significantly greater for intervention PLH compared to control PLH: alcohol and/or marijuana use, any substance use, hard drug use and a weighted index adjusting for seriousness of the drug. While the intervention-related reductions in substance use were larger among women than men, men also reduced their use. Compared to controls, gay and heterosexual men in the intervention reduced significantly their use of alcohol and marijuana, any substance, stimulants and the drug severity-weighted frequency of use index. Gay men also reduced their hard drug use significantly in the intervention compared to the control condition.

conclusionsA case management intervention model, delivered individually, is likely to result in significant and sustained reductions in substance use among PLH.

Indexed as

Risk Reduction BehaviorAdultAgedBehavior TherapyFemaleHIV InfectionsHumansMaleMiddle AgedPatient ComplianceSexual BehaviorSubstance Abuse, IntravenousTreatment OutcomeUnited States

Identifiers

PMID18494840
PMCPMC2665995
OpenAlexW1975118434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.