ArticlePLoS medicine2008
A user's guide to the NINDS rt-PA stroke trial database.
Article in PLoS medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Antiplatelet pretreatment and outcomes in intravenous thrombolysis for stroke: a systematic review and meta-analysis.Journal of neurology · 2017Pooled it
- Thrombolysis for acute ischaemic stroke.The Cochrane database of systematic reviews · 2014Pooled it
- TURN Score Predicts 24-Hour Cerebral Edema After IV Thrombolysis.Neurocritical care · 2016Trial
- Inclusion of Hospital Performance in Prehospital Stroke Routing: A Simulation Study.Prehospital emergency care · 2026Article
- Risk of selection bias assessment in the NINDS rt-PA stroke study.BMC medical research methodology · 2022Article
- Article
- Cost-Effectiveness of Bridging Anticoagulation Among Patients with Nonvalvular Atrial Fibrillation.Journal of general internal medicine · 2019Article
- Reducing age bias in decision analyses of anticoagulation for patients with nonvalvular atrial fibrillation - A microsimulation study.PloS one · 2018Article
- Minimal sufficient balance-a new strategy to balance baseline covariates and preserve randomness of treatment allocation.Statistical methods in medical research · 2015Article
- TURN Score Predicts 90-day Outcome in Acute Ischemic Stroke Patients After IV Thrombolysis.Neurocritical care · 2015Article
- TURN: A Simple Predictor of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis.Neurocritical care · 2015Article
- SAHIT Investigators--on the outcome of some subarachnoid hemorrhage clinical trials.Translational stroke research · 2013Review
- Article
- Use of recombinant tissue plasminogen activator in cancer patients with acute stroke.Journal of neuro-oncology · 2012Article
- A Pilot Trial of Low-Dose Intravenous Abciximab and Unfractionated Heparin for Acute Ischemic Stroke: Translating GP IIb/IIIa Receptor Inhibition to Clinical Practice.Translational stroke research · 2010Article
- Stroke: Measuring disease-free life after thrombolysis.Nature reviews. Neurology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.