ReviewWorld journal of gastroenterology2008
Mechanisms of biliary carcinogenesis and growth.
Review in World journal of gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 56 citations in OpenAlex.
- Epidemiologic transition of biliary tract cancers in an endemic region of Korea: insights from a regional cancer center cohort.BMC gastroenterology · 2026Observational
- Cholangiocarcinoma: Classification, Histopathology and Molecular Carcinogenesis.Pathology oncology research : POR · 2020Review
- Cholangiocarcinoma following external beam radiotherapy: A report of two cases.Oncology letters · 2017Article
- Cholangiocarcinoma: New InsightsAsian Pacific journal of cancer prevention : APJCP · 2017Review
- Increasing mortality in the United States from cholangiocarcinoma: an analysis of the National Center for Health Statistics Database.BMC gastroenterology · 2016Article
- Expression and activation of EGFR and STAT3 during the multistage carcinogenesis of intrahepatic cholangiocarcinoma induced by 3'-methyl-4 dimethylaminoazobenzene in rats.Journal of toxicologic pathology · 2015Article
- Gallbladder carcinoma in a pregnant patient with Crohn's disease complicated with gallbladder involvement.World journal of gastrointestinal oncology · 2013Article
- Impact of Salinomycin on human cholangiocarcinoma: induction of apoptosis and impairment of tumor cell proliferation in vitro.BMC cancer · 2012Article
- [Pathological anatomical characteristics of Klatskin tumors. Classification, current molecular biological aspects, prognosis factors].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2012Review
- Vitamin D3 regulates cell viability in gastric cancer and cholangiocarcinoma.Anatomy & cell biology · 2011Article
- Effect of 5-aminolevulinic acid-based photodynamic therapy via reactive oxygen species in human cholangiocarcinoma cells.International journal of nanomedicine · 2011Article
- Hilar cholangiocarcinoma: pathology and tumor biology.Frontiers of medicine in China · 2010Review
- A new variant of bile duct duplication with coexistence of distal cholangiocarcinoma.Nature reviews. Gastroenterology & hepatology · 2010Article
- New insights on cholangiocarcinoma.World journal of gastrointestinal oncology · 2010Article
- Molecular Markers in the Pathogenesis of Cholangiocarcinoma: Potential for Early Detection and Selection of Appropriate Treatment.Gastroenterology research · 2009Review
- Cholangiocarcinoma: estrogen-induced autocrine effects of VEGF on cell proliferation.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cholangiocarcinoma is a rare cancer originating from the neoplastic transformation of the epithelial cells (i.e. cholangiocytes) that line the biliary tract. The prognosis for patients with cholangiocarcinoma is grim due to lack of viable treatment options. The increase in world-wide incidence and mortality from cholangiocarcinoma highlights the importance of understanding the intracellular mechanisms that trigger the neoplastic transformation of cholangiocytes and the growth of biliary cancers. The purpose of the following review is to address what has been learned over the past decade concerning the molecular basis of cholangiocarcinogenesis. The material presented is divided into two sections: (1) mechanisms regulating neoplastic transformation of cholangiocytes; and (2) factors regulating cholangiocarcinoma growth. An understanding of the growth regulatory mechanisms of cholangiocarcinoma will lead to the identification of therapeutic targets for this devastating cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.