ReviewClinical reviews in allergy & immunology2008
Atypical cystic fibrosis and CFTR-related diseases.
Review in Clinical reviews in allergy & immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Carrier Screening Programs for Cystic Fibrosis, Fragile X Syndrome, Hemoglobinopathies and Thalassemia, and Spinal Muscular Atrophy: A Health Technology Assessment.Ontario health technology assessment series · 2023Pooled it
- Diagnosing Cystic Fibrosis in the 21st Century-A Complex and Challenging Task.Diagnostics (Basel, Switzerland) · 2024Review
- Article
- Article
- Cystic fibrosis associated with Wernicke's encephalopathy in an older adult.BMJ case reports · 2022Article
- Occurrence of Cystic Fibrosis Transmembrane Conductance Regulator Gene Mutations in Patients with Allergic Bronchopulmonary Aspergillosis Complicating Asthma.Mycopathologia · 2022Article
- A mesenchymal to epithelial switch in Fgf10 expression specifies an evolutionary-conserved population of ionocytes in salivary glands.Cell reports · 2022Article
- Atypical presentation of cystic fibrosis at 70 years of age.BMJ case reports · 2019Article
- Genome-first findings require precision phenotyping.Genetics in medicine : official journal of the American College of Medical Genetics · 2018Article
- Nasal Potential Difference to Quantify Trans-epithelial Ion Transport in Mice.Journal of visualized experiments : JoVE · 2018Article
- Exophiala dermatitidis Revealing Cystic Fibrosis in Adult Patients with Chronic Pulmonary Disease.Mycopathologia · 2018Article
- Role of CFTR mutation analysis in the diagnostic algorithm for cystic fibrosis.World journal of pediatrics : WJP · 2017Article
- Cystic fibrosis: a model system for precision medicine.Current opinion in pediatrics · 2016Review
- Repeatability and Diagnostic Value of Nasal Potential Difference in a Genetically Admixed Population.Journal of clinical medicine research · 2016Article
- Functional characteristics of L1156F-CFTR associated with alcoholic chronic pancreatitis in Japanese.American journal of physiology. Gastrointestinal and liver physiology · 2015Article
- A Genotypic-Oriented View of CFTR Genetics Highlights Specific Mutational Patterns Underlying Clinical Macrocategories of Cystic Fibrosis.Molecular medicine (Cambridge, Mass.) · 2015Article
- Diabetes and primary infertility in young males: do not forget cystic fibrosis.Clinical diabetes : a publication of the American Diabetes Association · 2015Article
- Rectal forceps biopsy procedure in cystic fibrosis: technical aspects and patients perspective for clinical trials feasibility.BMC gastroenterology · 2013Article
- Atypical cystic fibrosis: identification in the primary care setting.Canadian family physician Medecin de famille canadien · 2012Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cystic fibrosis (CF), which is among the most common life-shortening recessive illnesses, is caused by mutations of the CF transmembrane conductance regulator (CFTR) and typically involves chronic infection and progressive obstruction of the respiratory tract as well as pancreatic exocrine insufficiency. Disease severity, to some extent, correlates with organ sensitivity to CFTR dysfunction and to the amount of functional protein, which is influenced by the type of mutation. Atypical CF represents approximately 2% of affected individuals, and includes cases presenting in adolescence or adulthood with pancreatic exocrine sufficiency, normal or borderline sweat chloride concentrations, or with a single predominant clinical feature. This review briefly describes diagnostic methods and phenotypic characteristics of classic and atypical CF, as well as CFTR-related diseases, conditions in which mutated CFTR may contribute to the pathogenesis but do not strictly fit established diagnostic criteria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.