ArticlePloS one2008
Mitochondrial DNA haplogroup analysis reveals no association between the common genetic lineages and prostate cancer in the Korean population.
Article in PloS one, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- MtDNA meta-analysis reveals both phenotype specificity and allele heterogeneity: a model for differential association.Scientific reports · 2017Pooled it
- Spectrum of germline and somatic mitochondrial DNA variants in Tuberous Sclerosis Complex.Frontiers in genetics · 2022Article
- Association of mitochondrial haplogroup F with physical performance in Korean population.Genomics & informatics · 2019Article
- Contribution of Mitochondrial DNA Variation to Chronic Disease in East Asian Populations.Frontiers in molecular biosciences · 2019Review
- Mitochondrial biology and prostate cancer ethnic disparity.Carcinogenesis · 2018Review
- Mitochondrial genome variation and prostate cancer: a review of the mutational landscape and application to clinical management.Oncotarget · 2017Review
- Inherited mitochondrial DNA variants can affect complement, inflammation and apoptosis pathways: insights into mitochondrial-nuclear interactions.Human molecular genetics · 2014Article
- No association between typical European mitochondrial variation and prostate cancer risk in a Spanish cohort.Journal of human genetics · 2014Article
- mtDNA haplogroup and single nucleotide polymorphisms structure human microbiome communities.BMC genomics · 2014Article
- Mitochondrial DNA haplogroups and susceptibility to prostate cancer in a colombian population.ISRN oncology · 2014Article
- The awakening of an advanced malignant cancer: an insult to the mitochondrial genome.Biochimica et biophysica acta · 2012Review
- Japanese Alzheimer's disease and other complex disorders diagnosis based on mitochondrial SNP haplogroups.International journal of Alzheimer's disease · 2012Article
- Mitochondrial haplogroups and polymorphisms reveal no association with sporadic prostate cancer in a southern European population.PloS one · 2012Article
- Sequence-based polymorphisms in the mitochondrial D-loop and potential SNP predictors for chronic dialysis.PloS one · 2012Article
- The role of the mitochondrial genome in ageing and carcinogenesis.Journal of aging research · 2011Article
- Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients.American journal of human genetics · 2010Article
- Mitochondrial haplogroups associated with Japanese Alzheimer's patients.Journal of bioenergetics and biomembranes · 2009Article
- Association of mitochondrial DNA haplogroups with exceptional longevity in a Chinese population.PloS one · 2009Article
- Mitochondrial haplogroups and control region polymorphisms are not associated with prostate cancer in Middle European Caucasians.PloS one · 2009Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Mitochondrial DNA (mtDNA) variation has recently been suggested to have an association with various cancers, including prostate cancer risk, in human populations. Since mtDNA is haploid and lacks recombination, specific mutations in the mtDNA genome associated with human diseases arise and remain in particular genetic backgrounds referred to as haplogroups. To assess the possible contribution of mtDNA haplogroup-specific mutations to the occurrence of prostate cancer, we have therefore performed a population-based study of a prostate cancer cases and corresponding controls from the Korean population. No statistically significant difference in the distribution of mtDNA haplogroup frequencies was observed between the case and control groups of Koreans. Thus, our data imply that specific mtDNA mutations/lineages did not appear to have a significant effect on a predisposition to prostate cancer in the Korean population, although larger sample sizes are necessary to validate our results.
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Registered trials
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