Evidence map›Paper›PMID 1849230›Full record

ArticleMolecular and cellular biochemistry1991

Hexose metabolism in pancreatic islets: the glucose-6-phosphatase riddle.

M A Perales, A Sener, W J Malaisse

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Time-dependent mechanisms in beta-cell glucose sensing.Journal of biological physics · 2006
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

M A PeralesLaboratory of Experimental Medicine, Brussels Free University, Belgium.
A Sener
W J Malaisse
French Community of Belgium · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucose-6-phosphatase activity was measured in rat liver or pancreatic islet crude homogenates and microsomes. The data recorded in the liver were comparable to those reported in prior studies. However, in the islets, the hydrolysis of D-glucose 6-phosphate by disrupted microsomes represented, when expressed relative to the protein content, less than 2% of the value recorded in liver microsomes. Moreover, no phosphotransferase activity was detected in the islets. These findings impose reservation on both the presence of glucose-6-phosphatase in rat islets and its participation to stimulus-secretion coupling.

Indexed as

AnimalsFemaleGlucose-6-PhosphataseGlucose-6-PhosphateGlucosephosphatesIslets of LangerhansMicrosomesMicrosomes, LiverRatsRats, Inbred StrainsGlucose-6-PhosphataseGlucose-6-PhosphateGlucosephosphates

Identifiers

PMID1849230
OpenAlexW1990607115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.