Evidence map›Paper›PMID 18492296›Full record

SynthesisObstetrical & gynecological survey2008

Therapeutic amenorrhea in patients at risk for thrombocytopenia.

Meredith K Martin-Johnston, Olanma Y Okoji, Alicia Armstrong

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Obstetrical & gynecological survey, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Cancer Treatment-Related Ovarian Dysfunction in Women of Childbearing Potential: Management and Fertility Preservation Options.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Review
  2. Review
  3. Article
  4. Menstrual suppression: current perspectives.International journal of women's health · 2014
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Meredith K Martin-JohnstonIllinois Masonic Medical Center, Chicago, Illinois, USA.
Olanma Y Okoji
Alicia Armstrong
Advocate Illinois Masonic Medical Center · USGeorge Washington University · USNational Institutes of Health · US

Funding

Reproductive Endocrinology And Infertility Clinical Training ProgramZIAHD008737 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SEGARS, JAMES H. · 2009 to 2010
$3.2M
Intramural NIH HHS Z99 HD999999
6 · The paper itself

Abstract

To examine the need for and evaluate the method of menses suppression in women at risk for thrombocytopenia. A systematic review of the published literature in MEDLINE using the search terms thrombocytopenia, menorrhagia, therapeutic amenorrhea, progestin intrauterine device, combination oral contraceptive--extended and cyclic, gonadotropin releasing hormone agonist, danazol, and progestins. There are an increased number of reproductive age women at risk for thrombocytopenia who would benefit from menses suppression. A number of effective medical regimens are available. In patients who fail medical therapy, endometrial ablation appears to be effective in women with thrombocytopenia. As a result of the increased number of women at risk for thrombocytopenia, there is a need for therapeutic amenorrhea. The type of regimen selected depends upon the patients need for contraception and the ability to tolerate estrogen-containing medications. For women who fail medical therapy, there are surgical options, which are associated with less morbidity than hysterectomy.

Indexed as

AdultComorbidityContraceptive Agents, FemaleDanazolEstrogen AntagonistsFemaleGonadotropin-Releasing HormoneHematopoietic Stem Cell TransplantationHumansHysterectomyIntrauterine DevicesLevonorgestrelMenorrhagiaMenstruationThrombocytopeniaContraceptive Agents, FemaleDanazolEstrogen AntagonistsGonadotropin-Releasing HormoneLevonorgestrel

Identifiers

PMID18492296
PMCPMC4790444
OpenAlexW2010576319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.