ArticleHuman genetics2008
Genome-wide association analysis with selective genotyping identifies candidate loci for adult height at 8q21.13 and 15q22.33-q23 in Mongolians.
Article in Human genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Genomic prediction in pigs using data from a commercial crossbred population: insights from the Duroc x (Landrace x Yorkshire) three-way crossbreeding system.Genetics, selection, evolution : GSE · 2023Article
- Comprehensive genomic analyses associate UGT8 variants with musical ability in a Mongolian population.Journal of medical genetics · 2012Article
- Regions of homozygosity and their impact on complex diseases and traits.Human genetics · 2011Review
- Runs of homozygosity identify a recessive locus 12q21.31 for human adult height.The Journal of clinical endocrinology and metabolism · 2010Article
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13 authors.
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Abstract
We performed a genome-wide association study with 23,465 microsatellite markers to identify genes related to adult height. Selective genotyping was applied to extremely tall and extremely short individuals from the Khalkh-Mongolian population. Two loci, 8q21.13 and 15q22.33, which showed the strongest association with microsatellites were subjected to further analyses of SNPs in 782 tall and 773 short individuals. The most significant association was observed with SNP rs2220456 at 8q21.13 (P = 0.000016). In the LD block at 15q22.32, SNP rs8038652 located in intron 1 of IQCH was strongly associated (P = 0.0003), especially the AA genotype of the SNP under a recessive model was strongly associated with adult height (P = 0.000046).
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