ArticleStudies in mycology2007
What can comparative genomics tell us about species concepts in the genus Aspergillus?
Article in Studies in mycology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed.
- Article
- The KdmB-EcoA-RpdA-SntB (KERS) chromatin regulatory complex controls development, secondary metabolism and pathogenicity in Aspergillus flavus.Fungal genetics and biology : FG & B · 2023Article
- Deep Genotypic Species Delimitation ofJournal of fungi (Basel, Switzerland) · 2022Article
- Heterogeneity in the transcriptional response of the human pathogen Aspergillus fumigatus to the antifungal agent caspofungin.Genetics · 2022Article
- Chromatin profiling reveals heterogeneity in clinical isolates of the human pathogen Aspergillus fumigatus.PLoS genetics · 2022Article
- An Indian lineage of Histoplasma with strong signatures of differentiation and selection.Fungal genetics and biology : FG & B · 2022Article
- Cleaning the Cellular Factory-Deletion of McrA inFrontiers in fungal biology · 2021Article
- Functional Biology and Molecular Mechanisms of Host-Pathogen Interactions for Aflatoxin Contamination in Groundnut (Frontiers in microbiology · 2020Review
- Use of Dual RNA-seq for Systems Biology Analysis ofFrontiers in microbiology · 2020Article
- Evolution of Aspergillus oryzae before and after domestication inferred by large-scale comparative genomic analysis.DNA research : an international journal for rapid publication of reports on genes and genomes · 2019Article
- Review
- Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei.Applied microbiology and biotechnology · 2018Review
- Article
- Comparative transcriptomics of Aspergillus fumigatus strains upon exposure to human airway epithelial cells.Microbial genomics · 2018Article
- How a fungus shapes biotechnology: 100 years ofFungal biology and biotechnology · 2018Review
- Aflatoxins: Implications on Health.Indian journal of clinical biochemistry : IJCB · 2017Review
- Fungi as a Source of Food.Microbiology spectrum · 2017Review
- Article
- Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus.Genome biology · 2017Article
- A Comparison of Microsatellites in PhytopathogenicFrontiers in microbiology · 2017Article
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the nature of species" boundaries is a fundamental question in evolutionary biology. The availability of genomes from several species of the genus Aspergillus allows us for the first time to examine the demarcation of fungal species at the whole-genome level. Here, we examine four case studies, two of which involve intraspecific comparisons, whereas the other two deal with interspecific genomic comparisons between closely related species. These four comparisons reveal significant variation in the nature of species boundaries across Aspergillus. For example, comparisons between A. fumigatus and Neosartorya fischeri (the teleomorph of A. fischerianus) and between A. oryzae and A. flavus suggest that measures of sequence similarity and species-specific genes are significantly higher for the A. fumigatus - N. fischeri pair. Importantly, the values obtained from the comparison between A. oryzae and A. flavus are remarkably similar to those obtained from an intra-specific comparison of A. fumigatus strains, giving support to the proposal that A. oryzae represents a distinct ecotype of A. flavus and not a distinct species. We argue that genomic data can aid Aspergillus taxonomy by serving as a source of novel and unprecedented amounts of comparative data, as a resource for the development of additional diagnostic tools, and finally as a knowledge database about the biological differences between strains and species.
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