Evidence map›Paper›PMID 18490866›Full record

ArticleSexually transmitted diseases2008

Chlamydia trachomatis reinfection rates among female adolescents seeking rescreening in school-based health centers.

Charlotte A Gaydos, Catherine Wright, Billie Jo Wood, Gerry Waterfield, Sharon Hobson, Thomas C Quinn

Abstract read
In one paragraph

Article in Sexually transmitted diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Pathogenic and Protective Roles of Neutrophils inPathogens (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Determinants and prediction ofFrontiers in public health · 2022
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Interventions to prevent sexually transmitted infections, including HIV infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2011
    Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Charlotte A GaydosJohns Hopkins University, Baltimore, Maryland, USA. cgaydos@jhmi.edu
Catherine Wright
Billie Jo Wood
Gerry Waterfield
Sharon Hobson
Thomas C Quinn

Funding

HIV Prevention Trials Network: Network LaboratoryU01AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI ESHLEMAN, SUSAN H · 2006 to 2010
$16.5M
Immunopathogenesis Of Chlamydia trachomatis InfectionZIAAI000358 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI QUINN, THOMAS · 2009 to 2022
$7.0M
IMMUNOPATHOGENESIS OF CHLAMYDIA TRACHOMATIS INFECTIONSZ01AI000358 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI QUINN, THOMAS · 1985 to 2008
$745k
Intramural NIH HHS Z01 AI000358NIAID NIH HHS U01 AI068613
6 · The paper itself

Abstract

backgroundChlamydia trachomatis (CT) infections are common among adolescents attending high and middle schools. The study objective was to determine the reinfection rates of CT for females attending school-based health centers.

methodsAdolescents attending school-based health centers who reported they were sexually active were screened for CT using nucleic acid amplification tests on cervical or urine samples. Between 1996 and 2003, 10,609 female students were tested. The overall annual prevalence for unduplicated students in a calendar year ranged from 15.1% to 19.5%. Reinfection was defined as a positive test result occurring between 30 and 365 days after an initial positive result.

resultsThere were 897 female students who tested positive for CT and returned for at least 1 subsequent test between 30 and 365 days later. Of these, 236 had 1 or more subsequent positive tests for a cumulative incidence of reinfection in 1 year of 26.3% (95% confidence interval = 23.4-29.2%). Young age at first infection was significantly associated with increased risk of subsequent infection (P <0.01). Across sites, the cumulative incidence of reinfection in these female students ranged from 14.3% to 38.9%.

conclusionsThe chlamydia cumulative incidence of reinfection in these female adolescents attending high and middle schools was high and supports the Centers for Disease Control and Prevention recommendation to screen adolescents frequently, especially those with a history of a previous chlamydia infection.

Indexed as

Chlamydia trachomatisPatient Acceptance of Health CareAdolescentAdolescent Health ServicesAdultBaltimoreChlamydia InfectionsFemaleHumansIncidencePrevalenceRecurrenceRisk FactorsSchool Health ServicesUrinalysisWomen's Health

Identifiers

PMID18490866
PMCPMC2664683

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.