ReviewThe Journal of experimental biology2008
Ion channels in mammalian vestibular afferents may set regularity of firing.
Review in The Journal of experimental biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 75 citations in OpenAlex.
- Persistence of vestibular function in the absence of glutamatergic transmission from hair cells.Scientific reports · 2026Article
- A wide-ranging review of galvanic vestibular stimulation: from its genesis to basic science and clinical applications.Experimental brain research · 2025Review
- Molecular logic for cellular specializations that initiate the auditory parallel processing pathways.Nature communications · 2025Article
- Molecular logic for cellular specializations that initiate the auditory parallel processing pathways.bioRxiv : the preprint server for biology · 2024Article
- Pharmacological regeneration of sensory hair cells restores afferent innervation and vestibular function.The Journal of clinical investigation · 2024Article
- Using macular velocity measurements to relate parameters of bone conduction to vestibular compound action potential responses.Scientific reports · 2023Article
- How Peripheral Vestibular Damage Affects Velocity Storage: a Causative Explanation.Journal of the Association for Research in Otolaryngology : JARO · 2022Article
- Distinct neuronal types contribute to hybrid temporal encoding strategies in primate auditory cortex.PLoS biology · 2022Article
- Article
- Cholinergic Modulation of Membrane Properties of Calyx Terminals in the Vestibular Periphery.Neuroscience · 2021Article
- Similarities and Differences Between Vestibular and Cochlear Systems - A Review of Clinical and Physiological Evidence.Frontiers in neuroscience · 2021Review
- Exposure to Intense Noise Causes Vestibular Loss.Military medicine · 2020Article
- Ionic direct current modulation evokes spike-rate adaptation in the vestibular periphery.Scientific reports · 2019Article
- Models of vestibular semicircular canal afferent neuron firing activity.Journal of neurophysiology · 2019Review
- Article
- Semicircular canal biomechanics in health and disease.Journal of neurophysiology · 2019Review
- Synaptopathy as a Mechanism for Age-Related Vestibular Dysfunction in Mice.Frontiers in aging neuroscience · 2019Article
- Article
- Mathematical Modeling and Analyses of Interspike-Intervals of Spontaneous Activity in Afferent Neurons of the Zebrafish Lateral Line.Scientific reports · 2018Article
- Quantitative measurement of post-concussion syndrome Using Electrovestibulography.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Rodent vestibular afferent neurons offer several advantages as a model system for investigating the significance and origins of regularity in neuronal firing interval. Their regularity has a bimodal distribution that defines regular and irregular afferent classes. Factors likely to be involved in setting firing regularity include the morphology and physiology of the afferents' contacts with hair cells, which may influence the averaging of synaptic noise and the afferents' intrinsic electrical properties. In vitro patch clamp studies on the cell bodies of primary vestibular afferents reveal a rich diversity of ion channels, with indications of at least two neuronal populations. Here we suggest that firing patterns of isolated vestibular ganglion somata reflect intrinsic ion channel properties, which in vivo combine with hair cell synaptic drive to produce regular and irregular firing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.