Evidence map›Paper›PMID 18489197›Full record

ReviewPharmacoEconomics2008

Economic burden of heart failure in the elderly.

Lawrence Liao, Larry A Allen, David J Whellan

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in PharmacoEconomics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05928026 (Financial Support in an Underserved and Low-Income Population With Heart Failure), which is not on this map. Cited by 79 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 10 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05928026 nacompletednot on this mapstarted 2023, after this paper: background citation

Financial Support in an Underserved and Low-Income Population With Heart Failure

TypeinterventionalSponsorUniversity of Texas Southwestern Medical CenterRan2023 to 2025Enrolled153ConditionsHeart Failure, Systolic, Financial Stress, Medication Adherence, Quality of LifeArmsFinancial Support
3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 10 syntheses or guidelines pooled it, 208 citations in OpenAlex.

  1. Pooled it
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  12. Impact of Telemonitoring on Health Status.Circulation. Cardiovascular quality and outcomes · 2017
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  15. Article
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  18. Deep learning can predict cardiovascular events from liver imaging.JHEP reports : innovation in hepatology · 2025
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lawrence LiaoThe Duke Clinical Research Institute, Durham, NC, USA. liao0002@mc.duke.edu
Larry A Allen
David J Whellan
Clinical Research Institute · USLankenau Heart Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure (HF) ranks among the most costly chronic diseases in developed countries. At present these countries devote 1-2% of all healthcare expenditures towards HF. In the US, these costs are estimated at $US30.2 billion for 2007. The burden of HF is greatest among the elderly, with 80% of HF hospitalizations and 90% of HF-related deaths in this cohort. As a result, approximately three-quarters of the resources for HF care are consumed by elderly patients. As demographic shifts increase the number of elderly individuals in both developed and developing nations, the resources devoted to HF care will likely further increase. Hospitalization accounts for roughly two-thirds of HF costs, but procedures, outpatient visits and medications also consume significant financial resources. HF also adversely impacts patient quality of life, and these relevant effects may not be captured in pure cost analyses. The cost effectiveness of several pharmacological interventions has been explored. In general, neurohormonal antagonists used for outpatient treatment of chronic HF are relatively cost effective, in part by reducing hospitalizations. Because HF poses such an enormous financial burden, efficient resource allocation for its management is a major societal and governmental challenge. In order to make informed decisions and allocate resources for HF care rationally, detailed data regarding costs and resource use will be essential. Further studies are needed to examine the impact of pharmacological and non-pharmacological interventions on costs and resource use in elderly individuals with HF.

Indexed as

Cost of IllnessAgedDrug CostsHealth Care CostsHealth Care RationingHeart FailureHumans

Identifiers

PMID18489197
OpenAlexW2056514126

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.