Evidence map›Paper›PMID 18488415›Full record

ReviewInternational journal of nanomedicine2008

The mitochondrial genome, a growing interest inside an organelle.

Marco Crimi, Roberta Rigolio

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Mitochondrial heterogeneity in diseases.Signal transduction and targeted therapy · 2023
    Review
  3. Review
  4. Maternal-fetal genetic interactions, imprinting, and risk of placental abruption.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2022
    Article
  5. Review
  6. Complete mitochondrial genome of the Red Keelback (Mitochondrial DNA. Part B, Resources · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Sequencing and analysis of the complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2017
    Article
  12. Article
  13. Article
  14. Mitochondria in lung diseases.Expert review of respiratory medicine · 2013
    Review
  15. Article
  16. Genome-wide and candidate gene association studies of placental abruption.International journal of molecular epidemiology and genetics · 2013
    Article
  17. Article
  18. A case-control study of maternal blood mitochondrial DNA copy number and preeclampsia risk.International journal of molecular epidemiology and genetics · 2012
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marco CrimiNational Institute of Molecular Genetics (INGM), Functional Genomics Unit, Milan, Italy. crimi@ingm.it
Roberta Rigolio

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria are semi-autonomously reproductive organelles within eukaryotic cells carrying their own genetic material, called the mitochondrial genome (mtDNA). Until some years ago, mtDNA had primarily been used as a tool in population genetics. As scientists began associating mtDNA mutations with dozens of mysterious disorders, as well as the aging process and a variety of chronic degenerative diseases, it became increasingly evident that the information contained in this genome had substantial potential applications to improve human health. Today, mitochondria research covers a wide range of disciplines, including clinical medicine, biochemistry, genetics, molecular cell biology, bioinformatics, plant sciences and physiology. The present review intends to present a summary of the most exiting fields of the mitochondrial research bringing together several contributes in terms of original prospective and future applications.

Indexed as

Models, GeneticAnimalsDNA, MitochondrialGenetic Predisposition to DiseaseGenome, MitochondrialHumansMitochondrial DiseasesDNA, Mitochondrial

Identifiers

PMID18488415
PMCPMC2526360
OpenAlexW2287251910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.