ArticleCell2008
Giving space to cell signaling.
Article in Cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Exploring the influence of cytosolic and membrane FAK activation on YAP/TAZ nuclear translocation.Biophysical journal · 2021Article
- Article
- Multistability and dynamic transitions of intracellular Min protein patterns.Molecular systems biology · 2016Article
- Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis.Nature chemical biology · 2014Article
- cAMP signaling microdomains and their observation by optical methods.Frontiers in cellular neuroscience · 2014Review
- Computational model of VEGFR2 pathway to ERK activation and modulation through receptor trafficking.Cellular signalling · 2013Article
- Assessment of cellular mechanisms contributing to cAMP compartmentalization in pulmonary microvascular endothelial cells.American journal of physiology. Cell physiology · 2012Article
- The impact of long-term exposure to space environment on adult mammalian organisms: a study on mouse thyroid and testis.PloS one · 2012Article
- An adaptive coarse graining method for signal transduction in three dimensions.Fundamenta informaticae · 2012Article
- Reaction-diffusion systems in intracellular molecular transport and control.Angewandte Chemie (International ed. in English) · 2010Review
- Signalling ballet in space and time.Nature reviews. Molecular cell biology · 2010Review
- Spatially distributed cell signalling.FEBS letters · 2009Review
- Systems pathology--taking molecular pathology into a new dimension.Nature reviews. Clinical oncology · 2009Review
- Article
- Positional information generated by spatially distributed signaling cascades.PLoS computational biology · 2009Article
- Integrative physical oncology.Wiley interdisciplinary reviews. Systems biology and medicineReview
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spatial separation of component enzymes in a pathway creates microdomains and gradients of signaling activities. Imaging techniques and computational modeling help us to understand the complex relationships between signaling and spatial information. In this issue, Neves et al. (2008) report how the propagation of spatial information is controlled by the shape of hippocampal neurons and feedback and feed-forward motifs of the beta-adrenergic receptor signaling pathway.
Indexed as
Identifiers
18485861What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.