ReviewJournal of cellular physiology2008
Noncoding RNAs produced by oncogenic human herpesviruses.
Review in Journal of cellular physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 55 citations in OpenAlex.
- Genomic sequencing and comparative analysis of Epstein-Barr virus genome isolated from primary nasopharyngeal carcinoma biopsy.PloS one · 2012Trial
- Epstein-Barr virus-encoded microRNAs as regulators in host immune responses.International journal of biological sciences · 2018Review
- New insights into the expression and functions of the Kaposi's sarcoma-associated herpesvirus long noncoding PAN RNA.Virus research · 2016Review
- Review
- miR-28-3p is a cellular restriction factor that inhibits human T cell leukemia virus, type 1 (HTLV-1) replication and virus infection.The Journal of biological chemistry · 2015Article
- How do viruses trick B cells into becoming lymphomas?Current opinion in hematology · 2014Review
- Comprehensive profiling of Epstein-Barr virus-encoded miRNA species associated with specific latency types in tumor cells.Virology journal · 2013Article
- Molecular pathogenesis of B-cell posttransplant lymphoproliferative disorder: what do we know so far?Clinical & developmental immunology · 2013Review
- Epstein-Barr virus in the multiple sclerosis brain: a controversial issue--report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria.Brain : a journal of neurology · 2011Article
- Gammaherpesvirus and lymphoproliferative disorders in immunocompromised patients.Cancer letters · 2011Review
- Cellular gene expression that correlates with EBER expression in Epstein-Barr Virus-infected lymphoblastoid cell lines.Journal of virology · 2011Article
- Tegument protein control of latent herpesvirus establishment and animation.Herpesviridae · 2011Article
- lncRNAdb: a reference database for long noncoding RNAs.Nucleic acids research · 2011Article
- Article
- Characterization of Epstein-Barr virus miRNAome in nasopharyngeal carcinoma by deep sequencing.PloS one · 2010Article
- HIV-miR-H1 evolvability during HIV pathogenesis.Bio Systems · 2010Article
- EBV-positive Hodgkin lymphoma is associated with suppression of p21cip1/waf1 and a worse prognosis.Molecular cancer · 2010Article
- Current knowledge of MicroRNAs and noncoding RNAs in virus-infected cells.Methods in molecular biology (Clifton, N.J.) · 2010Article
- Mature and functional viral miRNAs transcribed from novel RNA polymerase III promoters.RNA (New York, N.Y.) · 2010Article
- How does Epstein-Barr virus (EBV) complement the activation of Myc in the pathogenesis of Burkitt's lymphoma?Seminars in cancer biology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The two human herpesviruses that are causally associated with cancer are Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus (KSHV). Both are lymphocryptoviruses that establish latency in B lymphocytes and persist for the lifetime of the host. EBV and KSHV are both linked to a variety of lymphomas. EBV is also a causative agent or cofactor in epithelial malignancies such as nasopharyngeal carcinoma whereas Kaposi's sarcoma is of endothelial cell origin. Both viruses encode a limited number of proteins during latent replication that are important for growth transformation and evasion of the immune system. In addition, they express noncoding RNAs during both latent and lytic infection. Many of these RNAs have been highly conserved during evolution and are expressed in a wide variety of clinical settings, suggesting their fundamental importance in the viral life cycle. The function of some of these RNAs such as the nuclear EBV EBER RNAs remains elusive although they are some of the most abundant transcripts produced by each virus. Both EBV and KSHV also have recently been shown to encode and express microRNAs. The study of these viral microRNAs is just beginning although several of their cellular and viral gene targets have been established. Viral microRNAs appear to be involved in both modulation of the immune response as well as oncogenesis. Because each target gene may have many microRNAs acting on its mRNA, and each microRNA may have more than one target, there are likely to be many new discoveries regarding the complex interactions of viral microRNAs and host cell genes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.