Evidence map›Paper›PMID 18483484›Full record

ReviewNature reviews. Microbiology2008

Coordinating assembly of a bacterial macromolecular machine.

Fabienne F V Chevance, Kelly T Hughes

Abstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 452 papers.

0numbers the graph read from it
0cells of the map it votes in
452citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

452 citing papers in PubMed.

  1. Indole decreases the virulence of enterotoxigenic Escherichia coli.World journal of microbiology & biotechnology · 2026
    Article
  2. Article
  3. Article
  4. Journal of bacteriology · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. The last bacterial common ancestor encoded a complex flagellum.bioRxiv : the preprint server for biology · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. The ancient E-ring in bacterial flagellar motors.FEMS microbiology reviews · 2026
    Review

392 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fabienne F V ChevanceDepartment of Biology, University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112, USA.
Kelly T Hughes

Funding

Coupling gene regulation to flagellar morphogenesisR01GM056141 · NIGMS · UNIVERSITY OF WASHINGTON · PI HUGHES, KELLY T · 1998 to 2023
$8.3M
Translational Control Coupled to Flagellum AssemblyR01GM062206 · NIGMS · UNIVERSITY OF WASHINGTON · PI HUGHES, KELLY T · 2001 to 2011
$1.7M
NIGMS NIH HHS GM056141NIGMS NIH HHS GM062206NIGMS NIH HHS R01 GM056141NIGMS NIH HHS R01 GM062206
6 · The paper itself

Abstract

The assembly of large and complex organelles, such as the bacterial flagellum, poses the formidable problem of coupling temporal gene expression to specific stages of the organelle-assembly process. The discovery that levels of the bacterial flagellar regulatory protein FlgM are controlled by its secretion from the cell in response to the completion of an intermediate flagellar structure (the hook-basal body) was only the first of several discoveries of unique mechanisms that coordinate flagellar gene expression with assembly. In this Review, we discuss this mechanism, together with others that also coordinate gene regulation and flagellar assembly in Gram-negative bacteria.

Indexed as

BacteriaBacterial ProteinsFlagellaFlagellinGene Expression Regulation, BacterialGenes, BacterialModels, BiologicalMolecular ChaperonesMultiprotein ComplexesBacterial ProteinsFlagellinFlgM protein, BacteriaMolecular ChaperonesMultiprotein Complexes

Identifiers

PMID18483484
PMCPMC5963726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.