Evidence map›Paper›PMID 18483053›Full record

ArticleBMJ (Clinical research ed.)2008

Grading quality of evidence and strength of recommendations for diagnostic tests and strategies.

Holger J Schünemann, A Holger J Schünemann, Andrew D Oxman, Jan Brozek, Paul Glasziou, Roman Jaeschke, Gunn E Vist, John W Williams, Regina Kunz, Jonathan Craig and 4 more

Erratum issued Registry-linked trialAbstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06762275 (Optimizing Management of Children Presenting With Acute Abdominal Pain in Primary Care), which is not on this map. Cited by 693 papers, 96 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
693citing papers in PubMed, 96 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06762275 narecruitingnot on this mapstarted 2025, after this paper: background citation

Optimizing Management of Children Presenting With Acute Abdominal Pain in Primary Care: a Cluster Randomized Controlled Trial Evaluating the Impact of a Clinical Prediction Rule Including C-reactive Protein for Appendicitis

TypeinterventionalSponsorUniversity Medical Center GroningenRan2025 to 2029Enrolled566ConditionsAppendicitis Acute, Acute Abdomen in ChildrenArmsDiagnostic strategy
3 · Its place in the literature

Who cites it

693 citing papers in PubMed, 96 syntheses or guidelines pooled it.

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  14. Luteal phase stimulation versus follicular phase stimulation in poor ovarian responders: A systematic review and a meta-analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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  20. Normative cerebellar tonsil position in healthy individuals: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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633 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
    Schünemann, A Holger J [corrected to Schünemann, Holger J]
5 · Who and what money

Authors and funding

14 authors.

Holger J SchünemannDepartment of Epidemiology, Italian National Cancer Institute Regina Elena, 00144 Rome, Italy. schuneh@mcmaster.ca
A Holger J Schünemann
Andrew D Oxman
Jan Brozek
Paul Glasziou
Roman Jaeschke
Gunn E Vist
John W Williams
Regina Kunz
Jonathan Craig
Victor M Montori
Patrick Bossuyt
Gordon H Guyatt
GRADE Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Evidence-Based MedicineBiasDiagnostic Tests, RoutineHealth Planning GuidelinesJudgmentOutcome Assessment, Health CarePractice Guidelines as TopicQuality of Health CareResearch DesignUnited Kingdom

Identifiers

PMID18483053
PMCPMC2386626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.