Evidence map›Paper›PMID 18482635›Full record

Trial reportHeart & lung : the journal of critical care

The impact of a highly visible display of cerebral perfusion pressure on outcome in individuals with cerebral aneurysms.

Catherine J Kirkness, Robert L Burr, Kevin C Cain, David W Newell, Pamela H Mitchell

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Heart & lung : the journal of critical care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Novel displays of patient information in critical care settings: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2019
    Pooled it
  3. Article
  4. Article
  5. Intracranial and blood pressure variability and long-term outcome after aneurysmal sub-arachnoid hemorrhage.American journal of critical care : an official publication, American Association of Critical-Care Nurses · 2009
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Catherine J KirknessBiobehavioral Nursing and Health Systems, University of Washington, Seattle, WA 98195-7266, USA.
Robert L Burr
Kevin C Cain
David W Newell
Pamela H Mitchell
University of Washington · US

Funding

CPP MANAGEMENT--INFORMATION FEEDBACK &NURSINGR01NR004901 · NINR · UNIVERSITY OF WASHINGTON · PI KIRKNESS, CATHERINE J · 1999 to 2007
$2.3M
NINR NIH HHS R01 NR004901NINR NIH HHS R01 NR04901
6 · The paper itself

Abstract

backgroundNurses' ability to rapidly detect decreases in cerebral perfusion pressure (CPP), which may contribute to secondary brain injury, may be limited by poor visibility of CPP displays.

objectiveTo evaluate the impact of a highly visible CPP display on the functional outcome in individuals with cerebral aneurysms.

methodsPatients with cerebral aneurysms (n = 100) who underwent continuous CPP monitoring were enrolled and randomized to beds with or without the additional CPP display. Six-month outcome was assessed.

resultsFunctional outcome was not significantly different between control and intervention groups after controlling for initial neurologic condition (odds ratio .904, 95% confidence interval 0.317 to 2.573). However, greater time below CPP thresholds (55 to 70 mm Hg) was significantly associated with poorer outcome (P = .005 to .010).

conclusionsAlthough the enhanced CPP display was not associated with significantly better outcome, longer periods of CPP below set levels were associated with poorer outcome.

Indexed as

Data DisplayPoint-of-Care SystemsAdultAgedAnalysis of VarianceBlood PressureBrainBrain IschemiaFemaleGlasgow Outcome ScaleHumansIntensive Care UnitsIntracranial AneurysmIntracranial PressureLogistic ModelsMale

Identifiers

PMID18482635
PMCPMC2497423
OpenAlexW2094972473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.