ReviewBiochemical Society transactions2008
Progress towards understanding the mechanism of cytokinesis in fission yeast.
Review in Biochemical Society transactions, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
- Steric hindrance in the upper 50 kDa domain of the motor Myo2p leads to cytokinesis defects in fission yeast.Journal of cell science · 2018Article
- Active force maintains the stability of a contractile ring.The European physical journal. E, Soft matter · 2017Article
- Comparative biology of cell division in the fission yeast clade.Current opinion in microbiology · 2015Review
- Article
- Tension modulates actin filament polymerization mediated by formin and profilin.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Immobile myosin-II plays a scaffolding role during cytokinesis in budding yeast.The Journal of cell biology · 2013Article
- Cell polarization and cytokinesis in budding yeast.Genetics · 2012Review
- Article
- Dividing the spoils of growth and the cell cycle: The fission yeast as a model for the study of cytokinesis.Cytoskeleton (Hoboken, N.J.) · 2011Review
- Transcriptomics of a giant freshwater prawn (Macrobrachium rosenbergii): de novo assembly, annotation and marker discovery.PloS one · 2011Article
- Cytoskeletal cross-linking and bundling in motor-independent contraction.Current biology : CB · 2010Review
- Making the cut: the chemical biology of cytokinesis.ACS chemical biology · 2010Review
- Cytokinesis and the contractile ring in fission yeast: towards a systems-level understanding.Trends in microbiology · 2010Review
- Roles of formin nodes and myosin motor activity in Mid1p-dependent contractile-ring assembly during fission yeast cytokinesis.Molecular biology of the cell · 2009Article
- Phylogenetic analysis identifies many uncharacterized actin-like proteins (Alps) in bacteria: regulated polymerization, dynamic instability and treadmilling in Alp7A.Molecular microbiology · 2009Article
- Ubiquitin-mediated degradation of the formin mDia2 upon completion of cell division.The Journal of biological chemistry · 2009Article
- Sending signals dynamically.Science (New York, N.Y.) · 2009Review
- Cloning of profilin (FcPFN) from the shrimp Fenneropenaeus chinensis, a highly expressed protein in white spot syndrome virus (WSSV)-infected shrimp.Journal of applied genetics · 2009Article
- Redistribution of actin during assembly and reassembly of the contractile ring in grasshopper spermatocytes.PloS one · 2009Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
We use fission yeast to study the molecular mechanism of cytokinesis. We benefit from a long history in genetic analysis of the cell cycle in fission yeast, which provided the most complete inventory of cytokinesis proteins. We used fluorescence microscopy of proteins tagged with fluorescent proteins to establish the temporal and spatial pathway for the assembly and constriction of the contractile ring. We combined biochemical analysis of purified proteins (myosin-II, profilin, formin Cdc12p and cofilin), observations of fluorescent fusion proteins in live cells and mathematical modelling to formulate and test a simple hypothesis for the assembly of the contractile ring. This model involves the formation of 65 nodes containing myosin-II and formin Cdc12p around the equator of the cell. As a cell enters anaphase, actin filaments grow from formin Cdc12p in these nodes. Myosin captures actin filaments from adjacent nodes and pulls intermittently to condense the nodes into a contractile ring.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.