Evidence map›Paper›PMID 18481164›Full record

ArticleJournal of genetic counseling2008

Health behaviors and psychological distress in women initiating BRCA1/2 genetic testing: comparison with control population.

Michel Dorval, Karine Bouchard, Elizabeth Maunsell, Marie Plante, Jocelyne Chiquette, Stéphanie Camden, Michel J Dugas, Jacques Simard, INHERIT BRCAs

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of genetic counseling, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Psychological aspects, risk and protective factors related to BRCA genetic testing: a review of the literature.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
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  20. Genetics: breast cancer as an exemplar.The Nursing clinics of North America · 2009
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michel DorvalFaculté de pharmacie, Université Laval, Québec, Canada. mdorval@uresp.ulaval.ca
Karine Bouchard
Elizabeth Maunsell
Marie Plante
Jocelyne Chiquette
Stéphanie Camden
Michel J Dugas
Jacques Simard
INHERIT BRCAs

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study objective was to compare breast cancer screening practices, lifestyle behaviors and psychological distress among 640 women initiating BRCA1/2 testing to those among 9,498 similarly-aged women from the general population. Health behaviors and psychological distress were reported in a self-administered questionnaire at pre-test genetic counseling. Regression analyses indicate that high-risk women were more frequently performing breast cancer screening and, in the case of those previously diagnosed with cancer, were more likely to be non-smokers and physically active than women from general population. However, women initiating BRCA1/2 testing were significantly more distressed than controls. Globally, high-risk women seemed to be well informed about recommendations for women who are at high risk and to have access to screening adapted to their risk level. Given their significant psychological distress, providing minimal psychosocial support to all women undergoing BRCA1/2 testing at pre-test genetic counseling is relevant.

Indexed as

Genes, BRCA1Genes, BRCA2Health BehaviorStress, PsychologicalAdultAgedAged, 80 and overCase-Control StudiesFemaleGenetic Predisposition to DiseaseGenetic TestingHumansLife StyleMiddle AgedRegression AnalysisSurveys and Questionnaires

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.