ArticleEuropean journal of applied physiology2008
Effects of recovery time on phosphocreatine kinetics during repeated bouts of heavy-intensity exercise.
Article in European journal of applied physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 33 citations in OpenAlex.
- Effects of different rest intervals following postactivation performance enhancement on multiple components of performance-related fitness in elite athletes.Journal of exercise rehabilitation · 2026Article
- A systematic review of the relationship between muscle oxygen dynamics and energy rich phosphates. Can NIRS help?BMC sports science, medicine & rehabilitation · 2024Article
- In-vivoAnalytical biochemistry · 2017Review
- DynamicNMR in biomedicine · 2016Article
- Changes in phosphocreatine concentration of skeletal muscle during high-intensity intermittent exercise in children and adults.European journal of applied physiology · 2013Article
- Comparing localized and nonlocalized dynamic 31P magnetic resonance spectroscopy in exercising muscle at 7 T.Magnetic resonance in medicine · 2012Article
- Warm-up effects on muscle oxygenation, metabolism and sprint cycling performance.European journal of applied physiology · 2012Article
- Mitochondrial oxidative phosphorylation is impaired in patients with congenital lipodystrophy.The Journal of clinical endocrinology and metabolism · 2012Article
- Effects of ammonium chloride ingestion on phosphocreatine metabolism during moderate- and heavy-intensity plantar-flexion exercise.European journal of applied physiology · 2010Article
- Application of the principles of systems biology and Wiener's cybernetics for analysis of regulation of energy fluxes in muscle cells in vivo.International journal of molecular sciences · 2010Review
- Functional assessment of skeletal muscle in intact mice lacking myostatin by concurrent NMR imaging and spectroscopy.Gene therapy · 2010Article
- Phosphocreatine recovery kinetics following low- and high-intensity exercise in human triceps surae and rat posterior hindlimb muscles.American journal of physiology. Regulatory, integrative and comparative physiology · 2009Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to examine the kinetics of phosphocreatine (PCr) breakdown in repeated bouts of heavy-intensity exercise separated by three different durations of resting recovery. Healthy young adult male subjects (n = 7) performed three protocols involving two identical bouts of heavy-intensity dynamic plantar flexion exercise separated by 3, 6, and 15 min of rest. Muscle high-energy phosphates and intracellular acid-base status were measured using phosphorus-31 magnetic resonance spectroscopy. In addition, the change in concentration of total haemoglobin (Delta[Hb(tot)]) and deoxy-haemoglobin (Delta[HHb]) were monitored using near-infrared spectroscopy. Prior exercise resulted in an elevated (P < 0.05) intracellular hydrogen ion ([H(+)](i)) after 3 min (182 +/- 72 (SD) nM; pH 6.73) and 6 min (112 +/- 19 nM; pH 6.95) but not after 15 min (93 +/- 8 nM; pH 7.03) compared to pre-exercise in Con (90 +/- 3 nM; pHi 7.05). The on-transient time constant (tau) of the PCr primary component was not different amongst the exercise bouts. However, in each of the subsequent bouts the amplitude of the PCr slow component, total PCr breakdown, and rise in [H(+)](i) were reduced (P < 0.05). At exercise onset, Delta[Hb(tot)] was increased (P < 0.05) and the Delta[HHb] kinetic response was slowed (P < 0.05) in the exercise after 3 min, consistent with improved muscle perfusion. In summary, neither the level of acidosis or muscle perfusion at the onset of exercise appeared to be directly related to the time course of the on-transient PCr primary component or the magnitude of the PCr slow component during subsequent bouts of exercise.
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