ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2008
High-frequency whisker vibration is encoded by phase-locked responses of neurons in the rat's barrel cortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Article
- Encoding of Vibrotactile Stimuli by Mechanoreceptors in Rodent Glabrous Skin.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Pre-neuronal processing of haptic sensory cues via dispersive high-frequency vibrational modes.Scientific reports · 2023Article
- Vibrotactile stimulation at gamma frequency mitigates pathology related to neurodegeneration and improves motor function.Frontiers in aging neuroscience · 2023Article
- Effects of optogenetic inhibition of a small fraction of parvalbumin-positive interneurons on the representation of sensory stimuli in mouse barrel cortex.Scientific reports · 2022Article
- Physiological noise facilitates multiplexed coding of vibrotactile-like signals in somatosensory cortex.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Of mice and monkeys: Somatosensory processing in two prominent animal models.Progress in neurobiology · 2021Review
- Millisecond precision temporal encoding of stimulus features during cortically generated gamma oscillations in the rat somatosensory cortex.The Journal of physiology · 2018Article
- Altered resonance properties of somatosensory responses in mice deficient for the schizophrenia risk gene Neuregulin 1.Brain structure & function · 2016Article
- Sensory encoding in Neuregulin 1 mutants.Brain structure & function · 2016Article
- EEG frequency tagging to explore the cortical activity related to the tactile exploration of natural textures.Scientific reports · 2016Article
- Study of the cortical representation of whisker frequency selectivity using voltage-sensitive dye optical imaging.Intravital · 2016Article
- Wideband phase locking to modulated whisker vibration point to a temporal code for texture in the rat's barrel cortex.Experimental brain research · 2015Article
- Multiple blocks of intermittent and continuous theta-burst stimulation applied via transcranial magnetic stimulation differently affect sensory responses in rat barrel cortex.The Journal of physiology · 2015Article
- Support for the slip hypothesis from whisker-related tactile perception of rats in a noisy environment.Frontiers in integrative neuroscience · 2015Article
- Tactile frequency discrimination is enhanced by circumventing neocortical adaptation.Nature neuroscience · 2014Article
- Theoretical foundations of the sound analog membrane potential that underlies coincidence detection in the barn owl.Frontiers in computational neuroscience · 2013Article
- Constant RMS versus constant peak modulation for the perceptual equivalence of sinusoidal amplitude modulated signals.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2013Article
- Multiplexing stimulus information through rate and temporal codes in primate somatosensory cortex.PLoS biology · 2013Article
- Parallel coding of first- and second-order stimulus attributes by midbrain electrosensory neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Rats perform texture discrimination during tactile exploration with their whiskers with high spatial and temporal precision. Although the peripheral mechanoreceptors provide tactile information with exquisite temporal resolution, physiological studies have suggested that this information might be lost at the cortical level. To address this discrepancy, multiunit and single-unit recordings were performed in the barrel cortex of isoflurane-anesthetized rats using continuous sinusoidal vibration of single whiskers at 15-700 Hz. In multiunit recordings, sustained phase-locked responses occurred up to vibration frequencies of 700 Hz, and 1:1 stimulus locking was observed up to 320 Hz. Wide-band responses of multiunits showed frequency encoding between 20 and 320 Hz. The discharge rates were not different for stimuli in the low- and high-frequency ranges, but they were significantly lower for non-phase-locked responses to high-frequency vibration. Response adaptation was present in only 25% of the cases, whereas in the majority of cases, entrainment to the vibratory frequency remained constant or even increased with stimulus duration. Increased entrainment to high-frequency stimulation was accompanied by the emergence of induced activity in the gamma-band range. Analysis of single-unit activity revealed that phase locking to vibratory stimuli was more precise than that observed for the multiunit responses. The results show that whisker vibrations at frequencies above 100 Hz are faithfully encoded by sustained phase-locked responses of cortical neurons under isoflurane anesthesia. It is conceivable that the awake animal makes use of the tactile signals at even much higher frequencies, which can be provided by the peripheral mechanoreceptors during texture discrimination.
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