ArticleBMC infectious diseases2008
Screening for tuberculosis infection among newly arrived asylum seekers: comparison of QuantiFERONTB Gold with tuberculin skin test.
Article in BMC infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Active and latent tuberculosis in refugees and asylum seekers: a systematic review and meta-analysis.BMC public health · 2020Pooled it
- Latent tuberculosis infection screening in immigrants to low-incidence countries: a meta-analysis.Molecular diagnosis & therapy · 2015Pooled it
- A systematic review on TST and IGRA tests used for diagnosis of LTBI in immigrants.Molecular diagnosis & therapy · 2015Pooled it
- Positivity rate of QuantiFERON-TB Gold PlusSAGE open medicine · 2026Article
- Comparing QuantiFERON-TB Gold Plus with Other Tests To Diagnose Mycobacterium tuberculosis Infection.Journal of clinical microbiology · 2019Observational
- Immigrant screening for latent tuberculosis infection: numbers needed to test and treat, a Norwegian population-based cohort study.BMJ open · 2019Article
- Health Status of Asylum Seekers, Spain.The American journal of tropical medicine and hygiene · 2018Article
- Immigrant screening for latent tuberculosis in Norway: a cost-effectiveness analysis.The European journal of health economics : HEPAC : health economics in prevention and care · 2017Article
- The impact of migration on tuberculosis epidemiology and control in high-income countries: a review.BMC medicine · 2016Review
- Implementation of an interferon-gamma release assay to screen for tuberculosis in refugees and immigrants.Journal of immigrant and minority health · 2013Article
- Screening for latent tuberculosis in Norwegian health care workers: high frequency of discordant tuberculin skin test positive and interferon-gamma release assay negative results.BMC public health · 2013Article
- Article
- Factors associated with latent tuberculosis among asylum seekers in Switzerland: a cross-sectional study in Vaud County.BMC infectious diseases · 2012Article
- Clustered tuberculosis in a low-burden country: nationwide genotyping through 15 years.Journal of clinical microbiology · 2012Article
- Screening of immigrants in the UK for imported latent tuberculosis: a multicentre cohort study and cost-effectiveness analysis.The Lancet. Infectious diseases · 2011Article
- A comparative examination of tuberculosis immigration medical screening programs from selected countries with high immigration and low tuberculosis incidence rates.BMC infectious diseases · 2011Article
- The role of entry screening in case finding of tuberculosis among asylum seekers in Norway.BMC public health · 2010Article
- Diagnosis and follow-up of treatment of latent tuberculosis; the utility of the QuantiFERON-TB Gold In-tube assay in outpatients from a tuberculosis low-endemic country.BMC infectious diseases · 2010Article
- Urinary tuberculosis: modern issues.Current urology reports · 2009Review
- Tuberculosis screening and follow-up of asylum seekers in Norway: a cohort study.BMC public health · 2009Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundQuantiFERONTB Gold (QFT) is a promising blood test for tuberculosis infection but with few data so far from immigrant screening. The aim of this study was to compare results of QFT and tuberculin skin test (TST) among newly arrived asylum seekers in Norway and to assess the role of QFT in routine diagnostic screening for latent tuberculosis infection.
methodsThe 1000 asylum seekers (age > or = 18 years) enrolled in the study were voluntarily recruited from 2813 consecutive asylum seekers arriving at the national reception centre from September 2005 to June 2006. Participation included a QFT test and a questionnaire in addition to the mandatory TST and chest X-ray.
resultsAmong 912 asylum seekers with valid test results, 29% (264) had a positive QFT test whereas 50% (460) tested positive with TST (indurations > or = 6 mm), indicating a high proportion of latent infection within this group. Among the TST positive participants 50% were QFT negative, whereas 7% of the TST negative participants were QFT positive. There was a significant association between increase in size of TST result and the likelihood of being QFT positive. Agreement between the tests was 71-79% depending on the chosen TST cut-off and it was higher for non-vaccinated individuals.
conclusionBy using QFT in routine screening, further follow-up could be avoided in 43% of the asylum seekers who would have been referred if based only on a positive TST (> or = 6 mm). The proportion of individuals referred will be the same whether QFT replaces TST or is used as a supplement to confirm a positive TST, but the number tested will vary greatly. All three screening approaches would identify the same proportion (88-89%) of asylum seekers with a positive QFT and/or a TST > or = 15 mm, but different groups will be missed.
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