Evidence map›Paper›PMID 18479406›Full record

ArticleHealth services research2008

Potential savings from an evidence-based consumer-oriented public education campaign on prescription drugs.

Julie M Donohue, Michael A Fischer, Haiden A Huskamp, Joel S Weissman

Abstract read
In one paragraph

Article in Health services research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Sources of regional variation in Medicare Part D drug spending.The New England journal of medicine · 2012
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julie M DonohueDepartment of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Crabtree Hall A613, Pittsburgh, PA 15261, USA.
Michael A Fischer
Haiden A Huskamp
Joel S Weissman

Funding

University of Pittsburgh Clinical and Translational Science InstitutionKL2TR000146 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$8.7M
NCATS NIH HHS KL2 TR000146
6 · The paper itself

Abstract

objectiveTo estimate potential savings associated with the Consumer Reports Best Buy Drugs program, a national educational program that provides consumers with price and effectiveness information on prescription drugs. DATA SOURCES: National data on 2006 prescription sales and retail prices paid for angiotensin-converting enzyme inhibitors (ACEIs), β-blockers, calcium channel blockers, and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-coA) reductase inhibitors (statins). STUDY

designWe converted national data on aggregate unit sales of drugs in the four classes to defined daily doses (DDD) and estimated a range of potential savings from generic and therapeutic substitution. PRINCIPAL

findingsWe estimated that $2.76 billion, or 7.83 percent of sales, could be saved if use of the drugs recommended by the educational program was increased. The recommended drugs' prices were 15-65 percent lower per DDD than their therapeutic alternatives. The majority (57.4 percent) of potential savings would be achieved through therapeutic substitution.

conclusionsSubstantial savings can be achieved through greater use of comparatively effective and lower cost drugs recommended by a national consumer education program. However, barriers to dissemination of consumer-oriented drug information must be addressed before savings can be realized.

Indexed as

Adrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsCalcium Channel BlockersCardiovascular AgentsCosts and Cost AnalysisDrug UtilizationEvidence-Based MedicineFees, PharmaceuticalHealth EducationHumansHydroxymethylglutaryl-CoA Reductase InhibitorsPrescription DrugsAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsCalcium Channel BlockersCardiovascular AgentsHydroxymethylglutaryl-CoA Reductase InhibitorsPrescription Drugs

Identifiers

PMID18479406
PMCPMC2653882

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.