Evidence map›Paper›PMID 18478332›Full record

ArticleDigestive diseases and sciences2008

Mannan-binding lectin levels related to spontaneous abortion in Brazilian patients with celiac disease.

Lorete Maria da Silva Kotze, Elisandra Grangeiro de Carvalho, Shirley Ramos da Rosa Utiyama, Renato Mitsunori Nisihara, Iara Messias-Reason

Abstract read
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In one paragraph

Article in Digestive diseases and sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Lorete Maria da Silva KotzeGastroenterology Service, Cajuru Hospital, Pontifical Catholic University of Paraná, Curitiba, Parana, Brazil.
Elisandra Grangeiro de Carvalho
Shirley Ramos da Rosa Utiyama
Renato Mitsunori Nisihara
Iara Messias-Reason
Hospital de Clínicas Universidade Federal do Paraná · BRUniversidade Federal do Paraná · BRPontifícia Universidade Católica do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low concentration of mannan-binding lectin (MBL) has been related to unexplained spontaneous abortion (SA), which has also been observed in an increased frequency in patients with celiac disease (CD). In this study, plasma levels of MBL were determined in patients with CD and irritable bowel syndrome (IBS) in order to investigate whether there is an association of MBL levels and the occurrence of SA in these patients. MBL concentration was determined in 46 patients with CD (28 without and 18 with report of SA) and 38 patients with IBS (25 without and 13 with report of SA). A higher frequency of SA was observed in women with CD when compared to IBS patients (23.2 vs. 13.9%; P = 0.046). No significant difference was observed in MBL concentrations between patients with CD, IBS, and healthy controls, nor between patients with or without occurrence of SA. These results suggest that the serum levels of MBL and the occurrence of SA in women with CD and IBS are not causally related.

Indexed as

Abortion, SpontaneousAdultAgedAged, 80 and overBrazilCase-Control StudiesCeliac DiseaseFemaleHealth SurveysHumansIrritable Bowel SyndromeMannose-Binding LectinMiddle AgedPregnancyPregnancy OutcomeProspective StudiesMannose-Binding Lectin

Identifiers

PMID18478332
OpenAlexW2056367725

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.