Evidence map›Paper›PMID 18477539›Full record

ReviewJournal of the Royal Society, Interface2008

Biomaterials for the central nervous system.

Yinghui Zhong, Ravi V Bellamkonda

Abstract readReview
In one paragraph

Review in Journal of the Royal Society, Interface, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Trial
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  6. Article
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  8. Review
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  11. Review
  12. Design Challenges in Polymeric Scaffolds for Tissue Engineering.Frontiers in bioengineering and biotechnology · 2021
    Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
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  20. Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yinghui ZhongNeurological Biomaterials and Therapeutics, Laboratory for Neuroengineering, Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta, GA 30332, USA.
Ravi V Bellamkonda

Funding

Bioengineered Scaffolds for Peripheral Nerve RepairR01NS044409 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI BELLAMKONDA, RAVI V. · 2002 to 2010
$2.2M
Strain-induced scarring &its effects on microelectrodesR01NS045072 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI BELLAMKONDA, RAVI V. · 2003 to 2008
$1.6M
Chondroitin Sulfate GAG Inhibition of Growth ConesR01NS043486 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI BELLAMKONDA, RAVI V. · 2003 to 2006
$1.3M
Neuro-integrative Coatings--Improved Neural RecordingsR01DC006849 · NIDCD · GEORGIA INSTITUTE OF TECHNOLOGY · PI BELLAMKONDA, RAVI V. · 2004 to 2007
$1.0M
NIDCD NIH HHS DC06849NIDCD NIH HHS R01 DC006849NINDS NIH HHS NS43486NINDS NIH HHS NS44409NINDS NIH HHS R01 NS043486NINDS NIH HHS R01 NS044409NINDS NIH HHS R01 NS045072NINDS NIH HHS R01 NS45072
6 · The paper itself

Abstract

Biomaterials are widely used to help treat neurological disorders and/or improve functional recovery in the central nervous system (CNS). This article reviews the application of biomaterials in (i) shunting systems for hydrocephalus, (ii) cortical neural prosthetics, (iii) drug delivery in the CNS, (iv) hydrogel scaffolds for CNS repair, and (v) neural stem cell encapsulation for neurotrauma. The biological and material requirements for the biomaterials in these applications are discussed. The difficulties that the biomaterials might face in each application and the possible solutions are also reviewed in this article.

Indexed as

AnimalsBiocompatible MaterialsCentral Nervous System DiseasesCerebrospinal Fluid ShuntsHumansHydrogelsInfusion Pumps, ImplantableProstheses and ImplantsBiocompatible MaterialsHydrogels

Identifiers

PMID18477539
PMCPMC2475552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.