Evidence map›Paper›PMID 18476673›Full record

ReviewChemical reviews2008

K+ channel modulators for the treatment of neurological disorders and autoimmune diseases.

Heike Wulff, Boris S Zhorov

Abstract readReview
In one paragraph

Review in Chemical reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Voltage Gated Ion Channels and Sleep.The Journal of membrane biology · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. KBiomedicines · 2023
    Review
  14. Article
  15. CaMolecules (Basel, Switzerland) · 2023
    Review
  16. Review
  17. Recombinant Expression inJournal of fungi (Basel, Switzerland) · 2022
    Article
  18. Article
  19. Article
  20. Review

48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Heike WulffDepartment of Pharmacology, University of California, Davis, California 95616, USA. hwulff@ucdavis.edu
Boris S Zhorov

Funding

The microglial potassium channels Kv1.3 and KCa3.1 as therapeutic targets for neuR01GM076063 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WULFF, HEIKE · 2006 to 2014
$2.5M
Small Molecule Kv1.3 Blockers as New Therapeutics for Multiple SclerosisR21NS053426 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WULFF, HEIKE · 2006 to 2007
$336k
NIGMS NIH HHS GM076063-01NIGMS NIH HHS R01 GM076063NINDS NIH HHS NS053426-01NINDS NIH HHS R21 NS053426
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAutoimmune DiseasesHumansInflammationNervous System DiseasesPotassium Channel BlockersPotassium ChannelsPotassium Channel BlockersPotassium Channels

Identifiers

PMID18476673
PMCPMC2714671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.