Evidence map›Paper›PMID 18476672›Full record

ReviewChemical reviews2008

Salvinorin A analogs as probes in opioid pharmacology.

Thomas E Prisinzano, Richard B Rothman

Abstract readReview
In one paragraph

Review in Chemical reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. O6C-20-nor-salvinorin A is a stable and potent KOR agonist.Bioorganic & medicinal chemistry letters · 2018
    Article
  11. A review of salvinorin analogs and their kappa-opioid receptor activity.Bioorganic & medicinal chemistry letters · 2018
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Collybolide is a novel biased agonist of κ-opioid receptors with potent antipruritic activity.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Thomas E PrisinzanoDepartment of Medicinal Chemistry, The University of Kansas, Lawrence, Kansas 66049, USA.
Richard B Rothman

Funding

Structure/Function Of Opioid Receptor/endorphin SystemZ01DA000121 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI ROTHMAN, RICHARD B · 1992 to 2008
$1.4M
Pharmacological Characterization of OpioidsZIADA000524 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI NEWMAN, AMY HAUCK · 2009 to 2012
$1.2M
Structure-Activity of Opioid DrugsZ01DA000525 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI ROTHMAN, RICHARD · 2008 to 2008
$598k
Intramural NIH HHS Z01 DA000121
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Analgesics, OpioidAnimalsDiterpenes, ClerodaneHumansProtein BindingProteinsStructure-Activity RelationshipAnalgesics, OpioidDiterpenes, ClerodaneProteinssalvinorin A

Identifiers

PMID18476672
PMCPMC2648615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.