Evidence map›Paper›PMID 18473420›Full record

ArticleWorld journal of gastroenterology2008

Cytomegalovirus colitis in a patient with Behcet's disease receiving tumor necrosis factor alpha inhibitory treatment.

Ismail Sari, Merih Birlik, Can Gonen, Servet Akar, Duygu Gurel, Fatos Onen, Nurullah Akkoc

Open access · hybridAbstract readCase Reports
In one paragraph

Article in World journal of gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Colitis associated with biological agents.World journal of gastroenterology · 2012
    Review
  10. Complications of tumor necrosis factor-α blockade in chronic granulomatous disease-related colitis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2010
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ismail SariDokuz Eylul Universitesi Tip Fakultesi Ic hastaliklari ABD Immunoloji-Romatoloji BD 35340 Inciralti, Izmir 35340, Turkey.
Merih Birlik
Can Gonen
Servet Akar
Duygu Gurel
Fatos Onen
Nurullah Akkoc
Dokuz Eylül University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-tumor necrosis factor alpha (TNF-alpha) inhibitors are effective in the treatment of various inflammatory rheumatic conditions. Increased risks of serious infections are the major issues concerning the long-term safety of these agents. We present a case of a young male Behcet's patient whose disease was complicated by cytomegalovirus (CMV) colitis. Colitis started 10 d after the third Infliximab dose and responded to the cessation of TNF blocking treatment and administration of ganciclovir. Tumor necrosis factor alpha and interferon gamma act at several levels in combating viral infections. CMV infections should be kept in mind and included in the differential diagnosis of severe gastrointestinal symptoms in patients receiving anti-TNF agents.

Indexed as

CytomegalovirusAdultAntibodies, MonoclonalAnti-Inflammatory AgentsAntiviral AgentsBehcet SyndromeColitisCytomegalovirus InfectionsGanciclovirHumansInfliximabMaleTumor Necrosis Factor-alphaAntibodies, MonoclonalAnti-Inflammatory AgentsAntiviral AgentsGanciclovirInfliximabTumor Necrosis Factor-alpha

Identifiers

PMID18473420
PMCPMC2710737
OpenAlexW2096384140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.