ArticleWorld journal of gastroenterology2008
Recent developments on the role of Clostridium difficile in inflammatory bowel disease.
Article in World journal of gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Article
- Uncommon Presentation of Clostridioides difficile in the Small Bowel: A Case Report and Review of Literature.Cureus · 2023Article
- Fecal Microbiota Transplant in Recurrent Clostridium Difficile Infections: A Systematic Review.Cureus · 2022Review
- Article
- Long-Term Safety and Efficacy of Fecal Microbiota Transplantation in the Treatment ofGastroenterology research · 2018Article
- Effects of β-lactam antibiotics and fluoroquinolones on human gut microbiota in relation to Clostridium difficile associated diarrhea.PloS one · 2014Article
- Clostridium difficile and inflammatory bowel disease: role in pathogenesis and implications in treatment.World journal of gastroenterology · 2013Review
- The intestinal microbiota dysbiosis and Clostridium difficile infection: is there a relationship with inflammatory bowel disease?Therapeutic advances in gastroenterology · 2013Article
- Campylobacter jejuni disrupts protective Toll-like receptor 9 signaling in colonic epithelial cells and increases the severity of dextran sulfate sodium-induced colitis in mice.Infection and immunity · 2012Article
- Clostridium difficile infection in Polish pediatric outpatients with inflammatory bowel disease.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2010Article
- Risk Factors for the Development of Clostridium difficile-associated Colitis after Colorectal Cancer Surgery.Journal of the Korean Society of Coloproctology · 2010Article
- The role of bacteria in the pathogenesis of inflammatory bowel disease.Gut and liver · 2010Article
- Review of medical and surgical management of Clostridium difficile infection.Techniques in coloproctology · 2010Review
- Clostridium difficile associated infection, diarrhea and colitis.World journal of gastroenterology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clostridium difficile (CD), specifically its toxins, have been implicated as a risk factor for exacerbation of the inflammatory process in up to 5% of patients with ulcerative colitis or Crohnos disease. Typical evidence of colonic changes with CD infection, including pseudomembranous exudate, are often not present; however, a severe clinical course may result, including precipitation of toxic colitis and toxic megacolon. Recently, hypervirulent CD strains have been reported raising concern for a more severe disease process in patients with underlying inflammatory bowel disease. Moreover, small bowel involvement or CD enteritis has been increasingly described, usually in those with a history of a prior colectomy or total proctocolectomy for prior severe and extensive inflammatory bowel disease. Finally, refractory or treatment-resistant pouchitis may occur with CD infection.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.