ArticleEndocrine2008
Herpes virus antibodies seroprevalence in children with autoimmune thyroid disease.
Article in Endocrine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- Study of Epstein-Barr virus serological profile in Egyptian patients with Hashimoto's thyroiditis: A case-control study.Journal of clinical & translational endocrinology · 2020Article
- Does the Epstein-Barr Virus Play a Role in the Pathogenesis of Graves' Disease?International journal of molecular sciences · 2019Article
- Investigation on the association between thyroid tumorigeneses and herpesviruses.Journal of endocrinological investigation · 2017Article
- Molecular mimicry and autoimmune thyroid disease.Reviews in endocrine & metabolic disorders · 2016Review
- A possible link between the Epstein-Barr virus infection and autoimmune thyroid disorders.Central-European journal of immunology · 2016Review
- Seroprevalence of HHV-6 and HHV-8 among blood donors in Greece.Virology journal · 2014Article
- Human cytomegalovirus and autoimmune disease.BioMed research international · 2014Review
- Lower CD28+ T cell proportions were associated with CMV-seropositivity in patients with Hashimoto's thyroiditis.BMC endocrine disorders · 2013Article
- Virologic and immunologic evidence supporting an association between HHV-6 and Hashimoto's thyroiditis.PLoS pathogens · 2012Article
- CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis.Autoimmune diseases · 2012Article
- Hypothyroidism - new aspects of an old disease.Hippokratia · 2010Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundElevated titers of antibodies against different herpes virus antigens have been reported in some immunodeficient and systemic autoimmune disorders.
objectiveTo examine if Herpes Simplex Virus (HSV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV) IgG and IgM antibodies are detected more frequently in children with autoimmune thyroid disease (AITD) compared to controls. SUBJECTS AND
methodsThirty-four children with AITD, aged 9.62 +/- 2.35 years, and 31 matched controls, aged 9.24 +/- 2.98 years, were studied.
resultsThe percentage of EBV IgG+ children with AITD was statistically higher than the percentage of EBV IgG+ controls (82.35% versus 51.61%, P = 0.008). The percentage of EBV IgG+ children with AITD and hypothyroidism was statistically higher than the percentage of EBV IgG+ children with AITD, without hypothyroidism (100% versus 70%, P = 0.024). No other statistically significant differences were observed in HSV-1+2, and CMV IgG or IgM antibodies between the subgroups of children studied.
conclusionsEBV seroprevalence is higher in children with AITD compared to controls and the underlying pathology remains to be elucidated.
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