ArticleNeurochemical research2008
Wiring and volume transmission in rat amygdala. Implications for fear and anxiety.
Article in Neurochemical research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Aberrant Fear: Biological Underpinnings Relevant to Psychosis, Antipsychotic Drugs, and Psychotherapeutic Treatments, a Translational Approach.International journal of molecular sciences · 2026Review
- Rat models of lactose intolerance: sexually dimorphic comorbidities with neuropsychiatric disorders modulated by tryptophan hydroxylase and the dopaminergic system.Scientific reports · 2025Article
- Lethal Interactions of neuronal networks in epilepsy mediated by both synaptic and volume transmission indicate approaches to prevention.Progress in neurobiology · 2025Review
- Relaxin-3 Innervation From the Nucleus Incertus to the Parahippocampal Cortex of the Rat.Frontiers in neuroanatomy · 2021Article
- Organic cation transporter 3 and the dopamine transporter differentially regulate catecholamine uptake in the basolateral amygdala and nucleus accumbens.The European journal of neuroscience · 2020Article
- A Novel Integrative Mechanism in Anxiolytic Behavior Induced by Galanin 2/Neuropeptide Y Y1 Receptor Interactions on Medial Paracapsular Intercalated Amygdala in Rats.Frontiers in cellular neuroscience · 2018Article
- Localization of the delta opioid receptor and corticotropin-releasing factor in the amygdalar complex: role in anxiety.Brain structure & function · 2017Article
- Comparative Distribution of Relaxin-3 Inputs and Calcium-Binding Protein-Positive Neurons in Rat Amygdala.Frontiers in neuroanatomy · 2016Article
- Direct targeting of peptidergic amygdalar neurons by noradrenergic afferents: linking stress-integrative circuitry.Brain structure & function · 2015Article
- Corticotropin releasing factor and catecholamines enhance glutamatergic neurotransmission in the lateral subdivision of the central amygdala.Neuropharmacology · 2013Article
- Cycling of dense core vesicles involved in somatic exocytosis of serotonin by leech neurons.Frontiers in physiology · 2012Article
- Extrasynaptic exocytosis and its mechanisms: a source of molecules mediating volume transmission in the nervous system.Frontiers in physiology · 2012Article
- GABA(A) ρ receptor mechanisms in the rat amygdala and its role in the modulation of fear and anxiety.Psychopharmacology · 2010Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The amygdala plays a key role in anxiety. Information from the environment reaches the amygdaloid basolateral nucleus and after its processing is relayed to the amygdaloid central nucleus where a proper anxiogenic response is implemented. Experimental evidence indicates that in this information transfer a GABAergic interface controls the trafficking of impulses between the two nuclei. Recent work indicates that interneuronal communication can take place by classical synaptic transmission (wiring transmission) and by volume transmission in which the neurotransmitter diffuses and flows through the extracellular space from its site of release and binds to extrasynaptic receptors at various distances from the source. Based on evidence from our laboratory the concept is introduced that neurotransmitters in the amygdala can modulate anxiety involving changes in fear learning and memories by effects on receptor mosaics in the fear circuits through wiring and volume transmission modes of communication.
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18473172What OpenQuestion holds
Registered trials
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