ArticleEnvironmental health perspectives2008
A cohort study of traffic-related air pollution impacts on birth outcomes.
Article in Environmental health perspectives, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02786420 (Imaging Innovations for Placental Assessment in Response to Environmental Pollution), which is not on this map. Cited by 231 papers, 11 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Imaging Innovations for Placental Assessment in Response to Environmental Pollution
Who cites it
231 citing papers in PubMed, 11 syntheses or guidelines pooled it, 620 citations in OpenAlex.
- Susceptible window identification of the relationship between maternal ozone exposure and preterm birth.International health · 2026Pooled it
- Association between atmospheric particulate matter pollution during pregnancy and premature birth in China: a meta-analysis.Frontiers in public health · 2025Pooled it
- Ozone exposure during early pregnancy and preterm birth: A systematic review and meta-analysis.Environmental research · 2021Pooled it
- Maternal fine particulate matter (PMEnvironmental science and pollution research international · 2019Pooled it
- Air pollution and female fertility: a systematic review of literature.Reproductive biology and endocrinology : RB&E · 2018Pooled it
- Different exposure levels of fine particulate matter and preterm birth: a meta-analysis based on cohort studies.Environmental science and pollution research international · 2017Pooled it
- Systematic literature review of reproductive outcome associated with residential proximity to polluted sites.International journal of health geographics · 2017Pooled it
- Occupational Exposure to Endocrine-Disrupting Chemicals and Birth Weight and Length of Gestation: A European Meta-Analysis.Environmental health perspectives · 2016Pooled it
- The association between fine particulate matter exposure during pregnancy and preterm birth: a meta-analysis.BMC pregnancy and childbirth · 2015Pooled it
- Maternal exposure to fine particulate matter (PM2.5) and pregnancy outcomes: a meta-analysis.Environmental science and pollution research international · 2015Pooled it
- A review and meta-analysis of outdoor air pollution and risk of childhood leukemia.Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews · 2015Pooled it
- Observational
- Long-Term PMLife (Basel, Switzerland) · 2025Review
- From the Atacama to Patagonia: Understanding the Effects of Extreme Temperatures on Birth Weight Across Climate Regions in Chile.GeoHealth · 2025Article
- Investigating inequalities in NOInternational journal for equity in health · 2025Article
- Article
- Effects of Combined Exercise Training on Modulating Fine Particulate Matter-Induced Skeletal Muscle Damage in Offspring Gestationally Exposed.Journal of cachexia, sarcopenia and muscle · 2025Article
- Assessing ambient air pollution's effects on birth outcomes: a Scottish IVF cohort study (2010 -2018).Environmental health : a global access science source · 2025Article
- Author correction: Association between exposure to particulate matter during pregnancy and birthweight: A systematic review and a meta-analysis of birth cohort studies.Journal of biomedical research · 2025Article
- Associations between satellite-derived estimates of PM2.5 species concentrations for organic carbon, elemental carbon, nitrate, and sulfate with birth weight and preterm birth in California during 2005-2014.Journal of exposure science & environmental epidemiology · 2025Article
171 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEvidence suggests that air pollution exposure adversely affects pregnancy outcomes. Few studies have examined individual-level intraurban exposure contrasts.
objectivesWe evaluated the impacts of air pollution on small for gestational age (SGA) birth weight, low full-term birth weight (LBW), and preterm birth using spatiotemporal exposure metrics.
methodsWith linked administrative data, we identified 70,249 singleton births (1999-2002) with complete covariate data (sex, ethnicity, parity, birth month and year, income, education) and maternal residential history in Vancouver, British Columbia, Canada. We estimated residential exposures by month of pregnancy using nearest and inverse-distance weighting (IDW) of study area monitors [carbon monoxide, nitrogen dioxide, nitric oxide, ozone, sulfur dioxide, and particulate matter < 2.5 (PM2.5) or < 10 (PM10) microm in aerodynamic diameter], temporally adjusted land use regression (LUR) models (NO, NO2, PM2.5, black carbon), and proximity to major roads. Using logistic regression, we estimated the risk of mean (entire pregnancy, first and last month of pregnancy, first and last 3 months) air pollution concentrations on SGA (< 10th percentile), term LBW (< 2,500 g), and preterm birth.
resultsResidence within 50 m of highways was associated with a 22% (95% CI, 0.81-1.87) [corrected] increase in LBW. Exposure to all air pollutants except O3 was associated with SGA, with similar odds ratios (ORs) for LUR and monitoring estimates (e.g., LUR: OR = 1.02; 95% CI, 1.00-1.04; IDW: OR = 1.05; 95% CI, 1.03-1.08 per 10-microg/m3 increase in NO). For preterm births, associations were observed with PM2.5 for births < 37 weeks gestation (and for other pollutants at < 30 weeks). No consistent patterns suggested exposure windows of greater relevance.
conclusionAssociations between traffic-related air pollution and birth outcomes were observed in a population-based cohort with relatively low ambient air pollution exposure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.