ArticleEnvironmental health perspectives2008
Effects of prenatal exposure to coal-burning pollutants on children's development in China.
Article in Environmental health perspectives, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 5 of them syntheses that pooled it.
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Who cites it
69 citing papers in PubMed, 5 syntheses or guidelines pooled it, 199 citations in OpenAlex.
- Impact of polycyclic aromatic hydrocarbon exposure on cognitive function and neurodegeneration in humans: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Effects of prenatal exposure to NOEnvironmental science and pollution research international · 2020Pooled it
- Impact of Coal-fired Power Plant Emissions on Children's Health: A Systematic Review of the Epidemiological Literature.International journal of environmental research and public health · 2019Pooled it
- Perinatal Exposure to Environmental Endocrine Disruptors in the Emergence of Neurodevelopmental Psychiatric Diseases: A Systematic Review.International journal of environmental research and public health · 2019Pooled it
- Global methylmercury exposure from seafood consumption and risk of developmental neurotoxicity: a systematic review.Bulletin of the World Health Organization · 2014Pooled it
- Developmental effects of exposures to environmental factors: the Polish Mother and Child Cohort Study.BioMed research international · 2013Trial
- Polycyclic aromatic hydrocarbons and perinatal outcomes: a scoping review.Pediatric research · 2026Review
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- Genotype-phenotypic correlation in a Chinese patient with isolated lissencephaly sequence caused by 17p13.3p13.2 chromosomal microdeletion: a 6-year follow-up study.Frontiers in genetics · 2026Article
- Externalizing behaviors in children living near coal-fired power plants.BMC public health · 2025Article
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- Air pollution exposures in early life and brain development in children (ABC): protocol for a pregnancy cohort study.BMJ paediatrics open · 2025Observational
- E-waste: mechanisms of toxicity and safety testing.FEBS open bio · 2024Review
- Prenatal exposure to polycyclic aromatic hydrocarbons and executive functions at school age: Results from a combined cohort study.International journal of hygiene and environmental health · 2024Article
- Exposure to coal ash and depression in children aged 6-14 years old.Environmental research · 2022Article
- Prenatal urinary metabolites of polycyclic aromatic hydrocarbons and toddler cognition, language, and behavior.Environment international · 2022Article
- Proximity to coal-fired power plants and neurobehavioral symptoms in children.Journal of exposure science & environmental epidemiology · 2022Article
- Maternal, neonatal and socio-economic factors associated with intellectual development among children from a coal mining region in Brazil.Environmental geochemistry and health · 2021Article
- Nail Samples of Children Living near Coal Ash Storage Facilities Suggest Fly Ash Exposure and Elevated Concentrations of Metal(loid)s.Environmental science & technology · 2021Article
9 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundEnvironmental pollutants such as polycyclic aromatic hydrocarbons (PAHs), lead, and mercury are released by combustion of coal and other fossil fuels.
objectivesIn the present study we evaluated the association between prenatal exposure to these pollutants and child development measured by the Gesell Developmental Schedules at 2 years of age.
methodsThe study was conducted in Tongliang, Chongqing, China, where a seasonally operated coal-fired power plant was the major source of ambient PAHs and also contributed lead and mercury to the air. In a cohort of nonsmoking women and their newborns enrolled between March 2002 and June 2002, we measured levels of PAH-DNA adducts, lead, and mercury in umbilical cord blood. PAH-DNA adducts (specifically benzo[a]pyrene adducts) provided a biologically relevant measure of PAH exposure. We also obtained developmental quotients (DQs) in motor, adaptive, language, and social areas.
resultsDecrements in one or more DQs were significantly associated with cord blood levels of PAH-DNA adducts and lead, but not mercury. Increased adduct levels were associated with decreased motor area DQ (p = 0.043), language area DQ (p = 0.059), and average DQ (p = 0.047) after adjusting for cord lead level, environmental tobacco smoke, sex, gestational age, and maternal education. In the same model, high cord blood lead level was significantly associated with decreased social area DQ (p = 0.009) and average DQ (p = 0.038).
conclusionThe findings indicate that exposure to pollutants from the power plant adversely affected the development of children living in Tongliang; these findings have implications for environmental health policy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.