Evidence map›Paper›PMID 18470300›Full record

Trial reportEnvironmental health perspectives2008

Para niños saludables: a community intervention trial to reduce organophosphate pesticide exposure in children of farmworkers.

Beti Thompson, Gloria D Coronado, Eric M Vigoren, William C Griffith, Richard A Fenske, John C Kissel, Jeffry H Shirai, Elaine M Faustman

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Environmental health perspectives, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
8.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Agricultural Worker Housing: A Review and a New Framework for Action.New solutions : a journal of environmental and occupational health policy : NS · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Characterizing the Neurodevelopmental Pesticide Exposome in a Children's Agricultural Cohort.International journal of environmental research and public health · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Characterization of organophosphate pesticides in urine and home environment dust in an agricultural community.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2018
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Beti ThompsonCancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. bthompso@fhcrc.org
Gloria D Coronado
Eric M Vigoren
William C Griffith
Richard A Fenske
John C Kissel
Jeffry H Shirai
Elaine M Faustman
University of Washington · USFred Hutch Cancer Center · US

Funding

STUDY OF CELLULAR &MOLECULAR ASPECTS OF PESTICIDE NEURODEVELOPMENTAL TOXICITYP01ES009601 · NIEHS · UNIVERSITY OF WASHINGTON · PI FAUSTMAN, ELAINE M · 1999 to 2013
$8.7M
NIEHS NIH HHS P01 ES009601NIEHS NIH HHS P01 ES09601
6 · The paper itself

Abstract

backgroundExposure to organophosphate (OP) pesticides is an occupational hazard for farmworkers and affects their children through the take-home pathway.

objectivesWe examined the effectiveness of a randomized community intervention to reduce pesticide exposure among farmworkers and their children.

methodsWe conducted a baseline survey of a cross-sectional sample of farmworkers (year 1) in 24 participating communities. Communities were randomized to intervention or control. After 2 years of intervention, a new cross-sectional survey of farmworkers was conducted (year 4). Farmworkers with a child 2-6 years of age were asked to participate in a substudy in which urine was collected from the farmworker and child, and dust was collected from the home and the vehicle driven to work.

resultsThe median concentration of urinary metabolites was higher in year 4 than in year 1 for dimethylthiophosphate (DMTP) and dimethyldithiophosphate in adults and for DMTP for children. There were significant increases within both the intervention and control communities between year 1 and year 4 (p < 0.005); however, the differences were not significant between study communities after adjusting for year (p = 0.21). The dust residue data showed azinphos-methyl having the highest percentage of detects in vehicles (86% and 84% in years 1 and 4, respectively) and in house dust (85% and 83% in years 1 and 4, respectively). There were no significant differences between intervention and control communities after adjusting for year (p = 0.49).

conclusionsWe found no significant decreases in urinary pesticide metabolite concentrations or in pesticide residue concentrations in house and vehicle dust from intervention community households compared with control community households after adjusting for baseline. These negative findings may have implications for future community-wide interventions.

Indexed as

AgricultureAdultChildChild, PreschoolCommunity NetworksCross-Sectional StudiesDustHousingHumansInterviews as TopicOccupational ExposureOrganophosphatesParent-Child RelationsPesticide ResiduesWashingtonDustOrganophosphatesPesticide Residueschildrencommunity interventionfarmworkersorganophosphate pesticidespesticide exposurerandomized trialrural community

Identifiers

PMID18470300
PMCPMC2367663
OpenAlexW2026901792

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.