Evidence map›Paper›PMID 18470273›Full record

ArticleReviews in urology2008

Superficial bladder cancer: an update on etiology, molecular development, classification, and natural history.

Erik Pasin, David Y Josephson, Anirban P Mitra, Richard J Cote, John P Stein

Registry-linked trialAbstract read
In one paragraph

Article in Reviews in urology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03664869 (Intravesical Instillation Therapy With Bacillus Calmette-Guérin), which is not on this map. Cited by 104 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03664869 phase3unknown statusnot on this mapstarted 2018, after this paper: background citation

Intravesical Instillation Therapy With Bacillus Calmette-Guérin (BCG) and Sequential BCG and Electromotive Mitomycin-C (EMDA-MCC) in Patients With High-risk Non-muscle-invasive Bladder Carcinoma

TypeinterventionalSponsorTurku University HospitalRan2018 to 2025Enrolled300ConditionsBladder CancerArmsBCG instillation therapy, Sequential BCG and EMDA mitomycin C
3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Observational
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  17. Bladder cancer.Nature reviews. Disease primers · 2023
    Review
  18. Review
  19. Article
  20. Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erik Pasin
David Y Josephson
Anirban P Mitra
Richard J Cote
John P Stein

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Superficial "non-muscle-invasive" bladder tumors represent a heterogeneous group of cancers, including those that are (1) papillary in nature and limited to the mucosa, (2) high grade and flat and confined to the epithelium, and (3) invasive into the submucosa, or lamina propria. The goal of treatment is 2-fold: (1) to reduce tumor recurrence and the subsequent need for additional therapies and the morbidity associated with these treatments and (2) to prevent tumor progression and the subsequent need for more aggressive therapy. This update reviews important contemporary concepts in the etiology, molecular mechanisms, classification, and natural history of superficial bladder cancer.

Indexed as

Bladder neoplasmsGenitourinary tumorsMolecular mechanismsNon-muscle-invasive tumorTransitional cell carcinoma

Identifiers

PMID18470273
PMCPMC2312342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.