ArticleApplied and environmental microbiology2008
Proteomic analysis of stationary phase in the marine bacterium "Candidatus Pelagibacter ubique".
Article in Applied and environmental microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Characterization of prokaryotic plankton community structure in the Southern East China Sea using combined 16S-rDNA and 16S-rRNA.Scientific reports · 2025Article
- Marine-Derived Fungi as a Valuable Resource for Amylases Activity Screening.Journal of fungi (Basel, Switzerland) · 2023Article
- A Reduction of Transcriptional Regulation in Aquatic Oligotrophic Microorganisms Enhances Fitness in Nutrient-Poor Environments.Microbiology and molecular biology reviews : MMBR · 2023Review
- Article
- Why Environmental Biomarkers Work: Transcriptome-Proteome Correlations and Modeling of Multistressor Experiments in the Marine BacteriumJournal of proteome research · 2022Article
- Isolation and identification of marine microbial products.Journal, genetic engineering & biotechnology · 2021Review
- SAR11 Cells Rely on Enzyme Multifunctionality To Metabolize a Range of Polyamine Compounds.mBio · 2021Article
- Characterization of a New M4 Metalloprotease With Collagen-Swelling Ability From MarineFrontiers in microbiology · 2020Article
- Impact of Ocean Acidification on the Intestinal Microbiota of the Marine Sea Bream (Frontiers in physiology · 2019Article
- Survival of the fewest: Microbial dormancy and maintenance in marine sediments through deep time.Geobiology · 2019Article
- Nutrient recycling facilitates long-term stability of marine microbial phototroph-heterotroph interactions.Nature microbiology · 2017Article
- Transcriptional Control in Marine Copiotrophic and Oligotrophic Bacteria with Streamlined Genomes.Applied and environmental microbiology · 2016Article
- Comparative Proteomic Analysis of Desulfotomaculum reducens MI-1: Insights into the Metabolic Versatility of a Gram-Positive Sulfate- and Metal-Reducing Bacterium.Frontiers in microbiology · 2016Article
- Marine-derived fungi: diversity of enzymes and biotechnological applications.Frontiers in microbiology · 2015Review
- Systems biology perspectives on minimal and simpler cells.Microbiology and molecular biology reviews : MMBR · 2014Review
- Incomplete Wood-Ljungdahl pathway facilitates one-carbon metabolism in organohalide-respiring Dehalococcoides mccartyi.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Development of an ecophysiological model for Diplosphaera colotermitum TAV2, a termite hindgut Verrucomicrobium.The ISME journal · 2013Article
- Giovannoni et al. reply.Nature · 2013Article
- The unique metabolism of SAR11 aquatic bacteria.Journal of microbiology (Seoul, Korea) · 2013Review
- A metaproteomic assessment of winter and summer bacterioplankton from Antarctic Peninsula coastal surface waters.The ISME journal · 2012Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
"Candidatus Pelagibacter ubique," an abundant marine alphaproteobacterium, subsists in nature at low ambient nutrient concentrations and may often be exposed to nutrient limitation, but its genome reveals no evidence of global regulatory mechanisms for adaptation to stationary phase. High-resolution capillary liquid chromatography coupled online to an LTQ mass spectrometer was used to build an accurate mass and time (AMT) tag library that enabled quantitative examination of proteomic differences between exponential- and stationary-phase "Ca. Pelagibacter ubique" cells cultivated in a seawater medium. The AMT tag library represented 65% of the predicted protein-encoding genes. "Ca. Pelagibacter ubique" appears to respond adaptively to stationary phase by increasing the abundance of a suite of proteins that contribute to homeostasis rather than undergoing a major remodeling of its proteome. Stationary-phase abundances increased significantly for OsmC and thioredoxin reductase, which may mitigate oxidative damage in "Ca. Pelagibacter," as well as for molecular chaperones, enzymes involved in methionine and cysteine biosynthesis, proteins involved in rho-dependent transcription termination, and the signal transduction enzyme CheY-FisH. We speculate that this limited response may enable "Ca. Pelagibacter ubique" to cope with ambient conditions that deprive it of nutrients for short periods and, furthermore, that the ability to resume growth overrides the need for a more comprehensive global stationary-phase response to create a capacity for long-term survival.
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