ArticleBiophysical journal2008
Magnitude of sarcomere extension correlates with initial sarcomere length during lengthening of activated single fibers from soleus muscle of rats.
Article in Biophysical journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Neuromechanical basis of region-specific differences and their implications for sport performance and injury prevention: a narrative review.European journal of applied physiology · 2025Review
- The role of transmembrane proteins on force transmission in skeletal muscle.Journal of biomechanics · 2014Article
- Rotator cuff tear reduces muscle fiber specific force production and induces macrophage accumulation and autophagy.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2012Article
- Non-uniform distribution of strain during stretch of relaxed skeletal muscle fibers from rat soleus muscle.Journal of muscle research and cell motility · 2011Article
- Decreased specific force and power production of muscle fibers from myostatin-deficient mice are associated with a suppression of protein degradation.Journal of applied physiology (Bethesda, Md. : 1985) · 2011Article
- Lateral transmission of force is impaired in skeletal muscles of dystrophic mice and very old rats.The Journal of physiology · 2011Article
- Pre-power stroke cross bridges contribute to force during stretch of skeletal muscle myofibrils.Proceedings. Biological sciences · 2008Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A laser-diffraction technique was developed that rapidly reports the lengths of sarcomeres (L(s)) in serially connected sectors of permeabilized single fibers. The apparatus translates a laser beam along the entire length of a fiber segment within 2 ms, with brief stops at each of 20 contiguous sectors. We tested the hypothesis that during lengthening contractions, when maximally activated fibers are stretched, sectors that contain the longer sarcomeres undergo greater increases in L(s) than those containing shorter sarcomeres. Fibers (n = 16) were obtained from the soleus muscles of adult male rats and the middle portions (length = 1.05 +/- 0.11 mm; mean +/- SD) were investigated. Single stretches of strain 27% and a strain rate of 54% s(-1) were initiated at maximum isometric stress and resulted in a 19 +/- 9% loss in isometric stress. The data on L(s) revealed that 1), the stretch was not distributed uniformly among the sectors, and 2), during the stretch, sectors at long L(s) before the stretch elongated more than those at short lengths. The findings support the hypothesis that during stretches of maximally activated skeletal muscles, sarcomeres at longer lengths are more susceptible to damage by excessive strain.
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Registered trials
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