ArticleAJNR. American journal of neuroradiology2008
Tract-based spatial statistics of diffusion tensor imaging in adults with dyslexia.
Article in AJNR. American journal of neuroradiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.
- Structural abnormalities in the dyslexic brain: a meta-analysis of voxel-based morphometry studies.Human brain mapping · 2013Pooled it
- Altering cortical connectivity: remediation-induced changes in the white matter of poor readers.Neuron · 2009Trial
- Patterns of the left thalamus embedding into the connectome associated with reading skills in children with reading disabilities.Network neuroscience (Cambridge, Mass.) · 2024Article
- SWADESH: a multimodal multi-disease brain imaging and neuropsychological database and data analytics platform.Frontiers in neurology · 2023Article
- A large-scale investigation of white matter microstructural associations with reading ability.NeuroImage · 2022Article
- Neuro-Behavioral Correlates of Executive Dysfunctions in Dyslexia Over Development From Childhood to Adulthood.Frontiers in psychology · 2021Review
- Developmental trajectories of white matter structure in children with and without reading impairments.Developmental cognitive neuroscience · 2019Article
- White matter alterations and tract lateralization in children with dyslexia and isolated spelling deficits.Human brain mapping · 2019Article
- White matter network connectivity deficits in developmental dyslexia.Human brain mapping · 2019Article
- Alterations in white matter pathways underlying phonological and morphological processing in Chinese developmental dyslexia.Developmental cognitive neuroscience · 2018Article
- Atypical White Matter Connectivity in Dyslexic Readers of a Fairly Transparent Orthography.Frontiers in psychology · 2018Article
- No evidence for systematic white matter correlates of dyslexia and dyscalculia.NeuroImage. Clinical · 2018Article
- Development of Tract-Specific White Matter Pathways During Early Reading Development in At-Risk Children and Typical Controls.Cerebral cortex (New York, N.Y. : 1991) · 2017Article
- Neurogenetics of developmental dyslexia: from genes to behavior through brain neuroimaging and cognitive and sensorial mechanisms.Translational psychiatry · 2017Review
- White matter integrity of cerebellar-cortical tracts in reading impaired children: A probabilistic tractography study.Brain and language · 2016Article
- Cerebellar white matter pathways are associated with reading skills in children and adolescents.Human brain mapping · 2015Article
- Neural correlates of language and non-language visuospatial processing in adolescents with reading disability.NeuroImage · 2014Article
- The DCDC2/intron 2 deletion and white matter disorganization: focus on developmental dyslexia.Cortex; a journal devoted to the study of the nervous system and behavior · 2014Article
- Individual differences in crossmodal brain activity predict arcuate fasciculus connectivity in developing readers.Journal of cognitive neuroscience · 2014Article
- Volumetric analysis of regional variability in the cerebellum of children with dyslexia.Cerebellum (London, England) · 2013Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
background and purposeDiffusion tensor imaging is a tool that can be used to study white matter microstructure in dyslexia. We tested the hypothesis that dyslexics have a white matter structural change (as measured by directional diffusion of water, which can be affected by disruption in white matter tracts) between brain regions that previous functional connectivity studies showed were associated with phonologic processing. MATERIALS AND
methodsDiffusion tensor imaging (DTI) scans were acquired from 7 healthy adult normal readers and from 14 adults with dyslexia on a 1.5T scanner. Voxelwise statistical analysis of the fractional anisotropy data were carried out by using Tract-Based Spatial Statistics to compare dyslexic subjects versus control subjects in white matter tracts.
resultsSignificant group difference map clusters (comparing adults with and without dyslexia) occurred in specific bilateral white matter tracts within the frontal lobe, temporal lobe, occipital lobe, and parietal lobe.
conclusionThe DTI fractional anisotropy results in the bilateral white matter showing higher fractional anisotropy in adult control subjects compared with adults with dyslexia (relating to white matter fiber tract integrity) are consistent with our previous functional connectivity results from seed points in the bilateral inferior frontal gyrus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.