ArticlePlant physiology2008
Involvement of CBF transcription factors in winter hardiness in birch.
Article in Plant physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 126 citations in OpenAlex.
- Chromatin remodeling at the C-REPEAT BINDING FACTOR cluster controls growth retardation at low ambient temperature.The Plant cell · 2026Article
- Genome-wide analysis of the CBF gene family and their transcriptional response to cold stress in Hibiscus mutabilis.Scientific reports · 2025Article
- The Brachypodium distachyon DREB transcription factor BdDREB-39 confers oxidative stress tolerance in transgenic tobacco.Plant cell reports · 2024Article
- Functional Divergence in Orthologous Transcription Factors: Insights from AtCBF2/3/1 and OsDREB1C.Molecular biology and evolution · 2024Article
- Transcriptome profiling of Bergenia purpurascens under cold stress.BMC genomics · 2023Article
- Identification and Analysis of theInternational journal of molecular sciences · 2023Article
- Integrated transcriptome and small RNA sequencing in revealing miRNA-mediated regulatory network of floral bud break inFrontiers in plant science · 2022Article
- Cold acclimation by the CBF-COR pathway in a changing climate: Lessons from Arabidopsis thaliana.Plant cell reports · 2019Review
- Phylogenetic, Molecular, and Functional Characterization of PpyCBF Proteins in Asian Pears (International journal of molecular sciences · 2019Article
- PpCBFs selectively regulate PpDAMs and contribute to the pear bud endodormancy process.Plant molecular biology · 2019Article
- Identification, Structural and Functional Characterization of Dormancy Regulator Genes in Apricot (Frontiers in plant science · 2019Article
- Isolation and functional characterization of thePhysiology and molecular biology of plants : an international journal of functional plant biology · 2018Article
- Environmentally Sensitive Molecular Switches Drive Poplar Phenology.Frontiers in plant science · 2018Review
- Modulation of Dormancy and Growth Responses in Reproductive Buds of Temperate Trees.Frontiers in plant science · 2018Review
- Rapid transcriptional and metabolic regulation of the deacclimation process in cold acclimated Arabidopsis thaliana.BMC genomics · 2017Article
- Genome sequencing and population genomic analyses provide insights into the adaptive landscape of silver birch.Nature genetics · 2017Article
- Physiological and transcriptomic analyses reveal a response mechanism to cold stress in Santalum album L. leaves.Scientific reports · 2017Article
- Perspective Research Progress in Cold Responses ofFrontiers in plant science · 2017Review
- A genetic genomics-expression approach reveals components of the molecular mechanisms beyond the cell wall that underlie peach fruit woolliness due to cold storage.Plant molecular biology · 2016Article
- An apple rootstock overexpressing a peach CBF gene alters growth and flowering in the scion but does not impact cold hardiness or dormancy.Horticulture research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cold acclimation of plants involves extensive reprogramming of gene expression. In Arabidopsis (Arabidopsis thaliana), three cold-inducible transcriptional activators designated CBF1 to -3/DREB1a to -c have been shown to play an important regulatory role in this acclimation process. Similarly to Arabidopsis, boreal zone trees can increase their freezing tolerance (FT) in response to low temperature during the growing season. However, maximal FT of these trees requires short daylength-induced dormancy development followed by exposure to both low and freezing temperatures. To elucidate the molecular basis of FT in overwintering trees, we characterized the role of birch (Betula pendula) CBF transcription factors in the cold acclimation process. We identified four putative CBF orthologs in a birch expressed sequence tag collection designated BpCBF1 to -4. Ectopic expression of birch CBFs in Arabidopsis resulted in constitutive expression of endogenous CBF target genes and increased FT of nonacclimated transgenic plants. In addition, these plants showed stunted growth and delayed flowering, typical features for CBF-overexpressing plants. Expression analysis in birch showed that BpCBF1 to -4 are low temperature responsive but differentially regulated in dormant and growing plants, the expression being delayed in dormant tissues. Freeze-thaw treatment, simulating wintertime conditions in nature, resulted in strong induction of BpCBF genes during thawing, followed by induction of a CBF target gene, BpLTI36. These results suggest that in addition to their role in cold acclimation during the growing season, birch CBFs appear to contribute to control of winter hardiness in birch.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.