Evidence map›Paper›PMID 18466475›Full record

ArticleBMC proceedings2007

Visualizing genotype x phenotype relationships in the GAW15 simulated data.

Xuejun Qin, Silke Schmidt, Eden Martin, Elizabeth R Hauser

Abstract read
In one paragraph

Article in BMC proceedings, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xuejun QinCenter for Human Genetics, Duke University Medical Center, Durham, NC 27710, USA. xqin@chg.duhs.duke.edu
Silke Schmidt
Eden Martin
Elizabeth R Hauser

Funding

Revealing Epistasis in Alzheimer DiseaseR01AG020135 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MARTIN, EDEN R. · 2002 to 2006
$2.7M
Statistical models for genetic studies of AMDR03EY015216 · NEI · DUKE UNIVERSITY · PI SCHMIDT, SILKE A · 2004 to 2005
$462k
NEI NIH HHS R03 EY015216NIA NIH HHS R01 AG020135
6 · The paper itself

Abstract

We have developed a graphical display tool called SIMLAPLOT for visualizing different ways in which continuous covariates may influence the genotype-specific risk for complex human diseases. The purpose of our study was to examine continuous covariates in the Genetic Analysis Workshop 15 simulated data set using our novel graphical display tool, with knowledge of the answers. The generated plots provide information about genetic models for the simulated continuous covariates and may help identify the single-nucleotide polymorphisms associated with the underlying quantitative trait loci.

Identifiers

PMID18466475
PMCPMC2367489

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.