ArticleJournal of proteome research2008
Protein disorder is positively correlated with gene expression in Escherichia coli.
Article in Journal of proteome research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Gene function predicts divergence across molecular levels.bioRxiv : the preprint server for biology · 2026Article
- Proteome-wide landscape of solubility limits in a bacterial cell.Scientific reports · 2022Article
- Tyrosine phosphorylation-dependent localization of TmaR that controls activity of a major bacterial sugar regulator by polar sequestration.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Exploring Potential Signals of Selection for Disordered Residues in Prokaryotic and Eukaryotic Proteins.Genomics, proteomics & bioinformatics · 2020Article
- Clusters of bacterial RNA polymerase are biomolecular condensates that assemble through liquid-liquid phase separation.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Structural Basis of the Subcellular Topology Landscape ofFrontiers in microbiology · 2019Article
- Arabidopsis Heat Stress-Induced Proteins Are Enriched in Electrostatically Charged Amino Acids and Intrinsically Disordered Regions.International journal of molecular sciences · 2018Article
- Cell-to-cell variation and specialization in sugar metabolism in clonal bacterial populations.PLoS genetics · 2017Article
- Intrinsic protein disorder reduces small-scale gene duplicability.DNA research : an international journal for rapid publication of reports on genes and genomes · 2017Article
- Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs).Chemical reviews · 2014Review
- Inactivation of the bacterial RNA polymerase due to acquisition of secondary structure by the ω subunit.The Journal of biological chemistry · 2013Article
- A decade and a half of protein intrinsic disorder: biology still waits for physics.Protein science : a publication of the Protein Society · 2013Review
- When a domain is not a domain, and why it is important to properly filter proteins in databases: conflicting definitions and fold classification systems for structural domains make filtering of such databases imperative.BioEssays : news and reviews in molecular, cellular and developmental biology · 2012Article
- Expanding the proteome: disordered and alternatively folded proteins.Quarterly reviews of biophysics · 2011Article
- Comparative proteome analysis of Helicobacter pylori clinical strains by two-dimensional gel electrophoresis.Journal of Zhejiang University. Science. B · 2011Article
- Cross-linking measurements of in vivo protein complex topologies.Molecular & cellular proteomics : MCP · 2011Article
- Cellular proteomes have broad distributions of protein stability.Biophysical journal · 2010Article
- Understanding protein non-folding.Biochimica et biophysica acta · 2010Review
- Insights into the regulation of intrinsically disordered proteins in the human proteome by analyzing sequence and gene expression data.Genome biology · 2009Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
We considered, on a global scale, the relationship between the predicted fraction of protein disorder and the RNA and protein expression in Escherichia coli. Fraction of protein disorder correlated positively with both measured RNA expression levels of E. coli genes in three different growth media and with predicted abundance levels of E. coli proteins. Though weak, the correlation was highly significant. Correlation of protein disorder with RNA expression did not depend on the growth rate of E. coli cultures and was not caused by a small subset of genes showing exceptionally high concordance in their disorder and expression levels. Global analysis was complemented by detailed consideration of several groups of proteins.
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Registered trials
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