ArticleInternational journal of hematology2008
Periostin and bone marrow fibrosis.
Article in International journal of hematology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Periostin in allergic rhinitis: from pathogenic mediator to predictive biomarker and therapeutic target.Frontiers in pharmacology · 2026Pooled it
- Analysis of Periostin, TGF-β, and SLUG Expression in Inflammatory Bowel Disease in Pediatric Patients and Their Clinical Implications.Journal of clinical medicine · 2026Article
- Differentially Expressed Proteins in Intra Synovial Compared to Extra Synovial Flexor Tendon Grafts in a Rabbit Tendon Transplantation Model.Biomedicines · 2020Article
- TGF-β1 Signaling and Tissue Fibrosis.Cold Spring Harbor perspectives in biology · 2018Review
- Periostin in Mature Stage Localized Scleroderma.Annals of dermatology · 2017Article
- Roles of Periostin in Respiratory Disorders.American journal of respiratory and critical care medicine · 2016Review
- Nifedipine and phenytoin induce matrix synthesis, but not proliferation, in intact human gingival connective tissue ex vivo.Journal of cell communication and signaling · 2015Article
- Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: potential role in liver fibrosis.Molecular immunology · 2015Article
- Biomarkers and severe asthma: a critical appraisal.Clinical and molecular allergy : CMA · 2015Review
- Possible involvement of TGF-β/periostin in fibrosis of right atrial appendages in patients with atrial fibrillation.International journal of clinical and experimental pathology · 2015Article
- Periostin as a tissue and urinary biomarker of renal injury in type 2 diabetes mellitus.PloS one · 2015Article
- Histamine contributes to tissue remodeling via periostin expression.The Journal of investigative dermatology · 2014Article
- The role of periostin in tissue remodeling across health and disease.Cellular and molecular life sciences : CMLS · 2014Review
- The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironment.Cell adhesion & migration · 2014Review
- Markers that can Reflect Asthmatic Activity before and after Reduction of Inhaled Corticosteroids: A Pilot Study.Biomarker insights · 2013Article
- Periostin: novel tissue and urinary biomarker of progressive renal injury induces a coordinated mesenchymal phenotype in tubular cells.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2012Article
- Effect of coating Straumann Bone Ceramic with Emdogain on mesenchymal stromal cell hard tissue formation.Clinical oral investigations · 2012Article
- Periostin facilitates skin sclerosis via PI3K/Akt dependent mechanism in a mouse model of scleroderma.PloS one · 2012Article
- Periostin modulates myofibroblast differentiation during full-thickness cutaneous wound repair.Journal of cell science · 2012Article
- An irradiation-altered bone marrow microenvironment impacts anabolic actions of PTH.Endocrinology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periostin is a secreted protein that shares structural homology with the insect axon guidance protein fasciclin 1. Periostin is expressed predominantly in collagen-rich fibrous connective tissues that are subjected to constant mechanical stresses. We have shown previously that periostin is a novel component of subepithelial fibrosis in bronchial asthma. Here, we investigated the relationship between periostin and bone marrow (BM) fibrosis. Periostin was expressed in the stroma and stromal cells of BM fibrosis specimens and to a great extent its expression levels correlated closely to the grade of fibrosis, as estimated by silver staining. However, in the present study, we found no relationship between plasma periostin levels and the extent of BM fibrosis. We also demonstrated that periostin is secreted by human BM hTERT stromal cells and that its secretion is enhanced by TGF-beta, a cytokine produced by clonal proliferation of megakaryocytes and/or monocytes. These results indicate that periostin is a component of BM fibrosis and that it may play a role in the disease progression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.