ArticleNature2008
Genome analysis of the platypus reveals unique signatures of evolution.
Article in Nature, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 307 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
307 citing papers in PubMed.
- Bibliometric Analysis of Milk Protein Gene Expression Regulation Using CiteSpace and VOSviewer.Molecular biotechnology · 2026Review
- GC content mismatch of transgene destabilizes RNA virus genomes.Journal of virology · 2026Article
- The evolution of structural variation across 500 million years of vertebrate evolution.bioRxiv : the preprint server for biology · 2026Article
- Conservation of NLRP3 Inflammasome Pathway in Monotremes and Large-Scale Restructuring of the Caspase-1 Gene Cluster Region in Mammals.Journal of molecular evolution · 2026Article
- Mechanisms driving resistance to oxidative stress during endometrial stromal cell decidualization†.Biology of reproduction · 2026Review
- Stable genome structures in living fossil fishes.Genome research · 2026Article
- Convergence and Parallelism of Phenotypic and Molecular Genetic Variability in Some Species.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2026Article
- A mechanical ratchet drives unilateral cytokinesis.Nature · 2026Article
- Insights into platypus crural gland transcriptomics - venom and beyond.BMC genomics · 2025Article
- AMHY and sex determination in egg-laying mammals.Genome biology · 2025Article
- Genome-Wide Microsatellite Characterization and Molecular Marker Development of Himalayan Griffon (Animals : an open access journal from MDPI · 2025Article
- Mammalian Species-Specific Resistance to Mammary Cancer.Journal of mammary gland biology and neoplasia · 2025Review
- The Spleen Virome of Australia's Endemic Platypus Is Dominated by Highly Diverse Papillomaviruses.Viruses · 2025Article
- Chromosome-level echidna genome illuminates evolution of multiple sex chromosome system in monotremes.GigaScience · 2025Article
- Marsupial cathelicidins: characterization, antimicrobial activity and evolution in this unique mammalian lineage.Frontiers in immunology · 2025Article
- Structural heterogeneity and functional convergence of transposable elements.Frontiers in genetics · 2025Article
- Molecular Evolution of theAnimals : an open access journal from MDPI · 2024Article
- Body fat and circulating leptin levels in the captive short-beaked echidna (Tachyglossus aculeatus).Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024Article
- Compensation of gene dosage on the mammalian X.Development (Cambridge, England) · 2024Review
- A family of olfactory receptors uniquely expanded in marsupial and monotreme genomes are expressed by a T cell subset also unique to marsupials and monotremes.Developmental and comparative immunology · 2024Article
247 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issuedNefedov, Mikhail [added]; de Jong, Pieter J [added]
Authors and funding
104 authors.
Funding
Abstract
We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a coat of fur adapted to an aquatic lifestyle; platypus females lactate, yet lay eggs; and males are equipped with venom similar to that of reptiles. Analysis of the first monotreme genome aligned these features with genetic innovations. We find that reptile and platypus venom proteins have been co-opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypus biology. Expansions of protein, non-protein-coding RNA and microRNA families, as well as repeat elements, are identified. Sequencing of this genome now provides a valuable resource for deep mammalian comparative analyses, as well as for monotreme biology and conservation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.