ArticleDigestive diseases and sciences2008
Infiltration of mast cells in rat colon is a consequence of ischemia/reperfusion.
Article in Digestive diseases and sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- The Effect of Albumin/Glutaraldehyde Glue (Bioglue) on Colonic Anastomosis Under Intestinal Obstruction: An Experimental Study in Rats.Journal of clinical medicine · 2025Article
- Mast Cells Modulate the Immune Response and Redox Status of the Gastrointestinal Tract in Induced Venom Pathogenesis.Inflammation · 2022Article
- Endoscopic full-thickness biopsy, a novel method in the work up of complicated abdominal symptoms.Therapeutic advances in gastroenterology · 2018Article
- The involvement of mast cells in the irinotecan-induced enteric neurons loss and reactive gliosis.Journal of neuroinflammation · 2017Article
- Long‑term follow‑up of buserelin‑induced enteric neuropathy in rats.Molecular medicine reports · 2016Article
- Structural and functional consequences of buserelin-induced enteric neuropathy in rat.BMC gastroenterology · 2014Article
- The role of mast cells in ischemia and reperfusion injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2014Review
- Mast cells: an expanding pathophysiological role from allergy to other disorders.Naunyn-Schmiedeberg's archives of pharmacology · 2012Review
- Mast cells drive mesenteric afferent signalling during acute intestinal ischaemia.The Journal of physiology · 2011Article
- The risk of ischaemic colitis in irritable bowel syndrome patients treated with serotonergic therapies.Drug safety · 2011Review
- Acute colonic ischaemia in rats results in long-term structural changes without alterations of colonic sensitivity.International journal of experimental pathology · 2008Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intestinal ischemia as well as mastocytosis occur in patients with inflammatory bowel disease and irritable bowel syndrome. Our aim was to clarify how ischemia with reperfusion (I/R) affects the structure, enteric neurons, and immune cells in the colon. Rats were subjected to colon ischemia for 1 h and reperfused for 1 day up to 20 weeks; sham-operated rats were used as controls. No structural remodeling of the intestinal segment was detected after I/R. The number and distribution of eosinophils were not affected by I/R. Local areas containing numerous mast cells were detected in the muscle layers, the serosa, and in and around the myenteric ganglia 4-20 weeks post ischemia. It was notable that myenteric ganglionic formations within mast-cell-rich areas virtually lacked neurons. Mast cells were rarely found in controls. In conclusion, I/R of the colon attracts mast cells, and death of myenteric neurons occurs in such locations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.