ArticleMolecules (Basel, Switzerland)2008
Effects of leucine-enkephalin on catalase activity and hydrogen peroxide levels in the haemolymph of the Pacific Oyster (Crassostrea gigas).
Article in Molecules (Basel, Switzerland), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 11 citations in OpenAlex.
- The Neuroendocrine-Immune Regulation in Response to Environmental Stress in Marine Bivalves.Frontiers in physiology · 2018Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The nervous and immune systems of invertebrates can exchange information through neuropeptides. Furthermore, some opioid peptides can function as endogenous immune system messengers and participate in the regulation of the immune responses. The present study was designed to investigate the effects of leucine-enkephalin (L-ENK) on the activity of catalase (CAT) and hydrogen peroxide (H(2)O(2)) content in the haemolymph of the Pacific Oyster (Crassostrea gigas). The CAT activity and H(2)O(2) content were investigated after the haemolymph of the species was exposed to 1, 5, and 50 microg/mL of LENK. The results indicate that the intracellular and extracellular CAT activity was increased with increasing concentration of L-ENK, while the intracellular and extracellular H(2)O(2) content was decreased with increasing concentration of L-ENK. L-ENK may regulate the intracellular and extracellular CAT activity and H2O2 content via binding with opioid neuropeptide receptors on immunocytes of the oysters. The data strongly suggests an involvement of opioid peptides in the regulation of the antioxidant defence systems of Crassostrea gigas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.